MmuEX7000940 @ mm10
Exon Skipping
Gene
ENSMUSG00000075318 | Scn2a
Description
sodium channel, voltage-gated, type II, alpha [Source:MGI Symbol;Acc:MGI:98248]
Coordinates
chr2:65707228-65713841:+
Coord C1 exon
chr2:65707228-65707360
Coord A exon
chr2:65711707-65711945
Coord C2 exon
chr2:65713668-65713841
Length
239 bp
Sequences
Splice sites
3' ss Seq
TTTATTTTTTTCCTCCCCAGAAC
3' ss Score
11.29
5' ss Seq
TTGGTAAGA
5' ss Score
8.85
Exon sequences
Seq C1 exon
GGCACAACTACTGAAACAGAAATAAGGAAGAGGAGGTCCAGTTCTTACCATGTTTCTATGGACTTGTTGGAAGACCCTACATCAAGGCAAAGAGCAATGAGTATGGCCAGCATTTTGACCAACACTATGGAAG
Seq A exon
AACTTGAAGAATCCAGACAGAAATGCCCTCCATGCTGGTATAAATTTGCTAATATGTGCCTGATTTGGGACTGTTGTAAGCCATGGCTAAAGGTAAAACATGTTGTCAATCTGGTAGTGATGGATCCATTCGTTGACCTGGCCATCACCATCTGCATTGTGTTAAATACACTCTTCATGGCCATGGAGCACTACCCGATGACGGAGCAGTTCAGCAGTGTGCTGTCTGTTGGGAATTTG
Seq C2 exon
GTCTTCACTGGGATCTTCACCGCAGAAATGTTTCTCAAGATAATAGCCATGGATCCATATTATTACTTTCAAGAAGGCTGGAATATCTTTGATGGCTTTATAGTGAGCCTTAGTTTAATGGAACTCGGCTTGGCGAATGTGGAAGGACTGTCAGTTCTCCGATCTTTCCGACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075318-'21-28,'21-21,26-28=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.449 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF119333=DUF3451=PD(16.5=82.2)
A:
PF0052026=Ion_trans=PU(1.6=3.8)
C2:
PF0052026=Ion_trans=FE(30.0=100)
Main Skipping Isoform:
ENSMUST00000028377fB3596
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GGCACAACTACTGAAACAGAAA
R:
CGGAGAACTGACAGTCCTTCC
Band lengths:
294-533
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types