BtaEX6016501 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000018010 | ABCA4
Description
ATP-binding cassette, sub-family A (ABC1), member 4 [Source:HGNC Symbol;Acc:HGNC:34]
Coordinates
chr3:49654294-49656001:+
Coord C1 exon
chr3:49654294-49654326
Coord A exon
chr3:49655692-49655797
Coord C2 exon
chr3:49655927-49656001
Length
106 bp
Sequences
Splice sites
3' ss Seq
ACTTCTTGTTCCCTTGTCAGGTA
3' ss Score
10.27
5' ss Seq
GGGGTATGT
5' ss Score
7.48
Exon sequences
Seq C1 exon
TTTGAAGAGCAAATTCTGGGTCAATGAACAGAG
Seq A exon
GTATGGAGGAATTTCTGTCGGAGGAAAGCTCCCAGCTCCCCCCTTCACTGGAGAAGCACTTGTTGGATTTTTAAGTGACCTTGGCCAGTTAATGAATGTGAGCGGG
Seq C2 exon
GGCCCTATGACCAGAGAGGCTGCTAAAGAAATGCCTGCTTTCCTTAAACAACTAGAAACTGAAGACAATATTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000018010-'40-33,'40-32,41-33=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.028 C2=0.040
Domain overlap (PFAM):
C1:
NO
A:
PF126982=ABC2_membrane_3=PU(7.0=63.9)
C2:
PF126982=ABC2_membrane_3=FE(7.3=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAGAGCAAATTCTGGGTCA
R:
TGTCTTCAGTTTCTAGTTGTTTAAGG
Band lengths:
98-204
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000567; ELM sequence: MNVSGG; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]