DreEX6095549 @ danRer10
Exon Skipping
Gene
ENSDARG00000057169 | abca4a
Description
ATP-binding cassette, sub-family A (ABC1), member 4a [Source:ZFIN;Acc:ZDB-GENE-050517-3]
Coordinates
chr24:28549583-28551856:+
Coord C1 exon
chr24:28549583-28549615
Coord A exon
chr24:28549745-28549850
Coord C2 exon
chr24:28551782-28551856
Length
106 bp
Sequences
Splice sites
3' ss Seq
TGTGTTTGTTTTTACTTCAGGTA
3' ss Score
10.28
5' ss Seq
GGGGTAAAT
5' ss Score
4.46
Exon sequences
Seq C1 exon
CCTGAAGAGCAAGTACTGGGTGAACGAACAAAG
Seq A exon
GTATGGTGGCATTTCTGTTGGAGGGCGACTTCCTGTTCTTAATTTGGATCCTAAATCCATTCAGAATGCAGCTGCTCAGATTGGACGCTTGCTTAATGTCACCGGG
Seq C2 exon
GGCAGATACTCAAAGCTTGCTCTGGACGAGTTTGCCACATTTCTGAGGTACATGGAGACTGAAAACAATGTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000057169-'39-40,'39-39,40-40=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=PU(2.9=83.3)
A:
PF126982=ABC2_membrane_3=FE(10.0=100)
C2:
PF126982=ABC2_membrane_3=FE(6.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGAAGAGCAAGTACTGGGTG
R:
TGACATTGTTTTCAGTCTCCATGT
Band lengths:
106-212
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000567; ELM sequence: MNVSGG; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]