DmeEX0007160 @ dm6
Exon Skipping
Gene
FBgn0000117 | arm
Description
The gene armadillo is referred to in FlyBase by the symbol Dmelarm (CG11579, FBgn0000117). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (2 unique). Gene sequence location is X:1891401..1900646. Its molecular function is described by 8 unique terms, many of which group under: binding; protein binding; transcription factor binding; enzyme binding; transcription regulator activity. It is involved in the biological process described with 35 unique terms, many of which group under: compound eye development; sensory system development; eye development; protein localization to adherens junction; regulation of biological quality. 147 alleles are reported. The phenotypes of these alleles manifest in: presumptive embryonic/larval central nervous system; cellular anatomical entity; adherens junction; anchoring junction; tracheal tip cell. The phenotypic classes of alleles include: phenotype; short lived; cell migration defective; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.
Coordinates
chrX:1895114-1900173:-
Coord C1 exon
chrX:1900044-1900173
Coord A exon
chrX:1898980-1899039
Coord C2 exon
chrX:1895114-1896753
Length
60 bp
Sequences
Splice sites
3' ss Seq
TCTCCGTCTCTTTCTTGCAGGTG
3' ss Score
14.06
5' ss Seq
CCAGTAAGT
5' ss Score
9.09
Exon sequences
Seq C1 exon
CATCGCTAGTTGGGTTTCGTCGCCATATACACAGTTTTTCTCGAGCAGACAATTCGCTGTTATTTTGTTTCTTATAGCGTTTTAAATAAATAAATCCTGCTCTAAAGCAGACTTAAATTCCTTGGACGCG
Seq A exon
GTGTGGTGTAAAGCGCCTCAATCACCAAGATGAGTTACATGCCAGCCCAGAATCGAACCA
Seq C2 exon
TGTCGCATAATAATCAATACAATCCACCTGATCTGCCGCCGATGGTATCCGCCAAGGAGCAGACCCTCATGTGGCAGCAGAATTCGTACTTGGGCGACTCCGGCATCCACTCGGGTGCCGTGACCCAGGTTCCATCGCTGTCTGGCAAGGAGGACGAGGAGATGGAGGGAGATCCACTTATGTTCGACCTGGACACCGGTTTCCCGCAGAATTTCACACAAGACCAAGTGGACGATATGAACCAGCAACTGAGCCAGACACGCTCCCAACGTGTACGTGCTGCCATGTTTCCGGAAACCCTGGAGGAGGGCATTGAGATTCCCTCCACCCAGTTTGATCCCCAACAGCCGACGGCAGTGCAACGTCTTTCGGAACCGTCACAAATGCTAAAGCACGCGGTGGTCAATCTGATCAACTACCAGGACGACGCTGAGCTGGCAACCAGGGCCATACCCGAGTTGATCAAGCTGCTGAACGATGAGGATCAGGTGGTAGTTTCC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0000117-'1-5,'1-4,8-5
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. ATG (>10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=1.000 C2=0.219
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
PF081677=RIX1=WD(100=33.6),PF0160215=Adaptin_N=WD(100=34.7),PF0051418=Arm=WD(100=7.5),PF0051418=Arm=WD(100=5.9),PF0051418=Arm=WD(100=7.9)
Main Inclusion Isoform:
FBpp0089031

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0089032, FBpp0089033, FBpp0089034, FBpp0089035, FBpp0304835
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCGAGCAGACAATTCGCTGT
R:
GATACCATCGGCGGCAGATC
Band lengths:
140-200
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)