DmeEX6000385 @ dm6
Exon Skipping
Gene
FBgn0023528 | CG2924
Description
This gene is referred to in FlyBase by the symbol DmelCG2924 (FBgn0023528). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:2264657..2270761. Its molecular function is described by: ubiquitin-protein transferase activity; ubiquitin conjugating enzyme activity. It is involved in the biological process described with: protein K48-linked ubiquitination; protein polyubiquitination. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chrX:2266820-2269704:-
Coord C1 exon
chrX:2268938-2269704
Coord A exon
chrX:2267177-2267293
Coord C2 exon
chrX:2266820-2267107
Length
117 bp
Sequences
Splice sites
3' ss Seq
TGCCTGTTTCTCTCCTGCAGGAA
3' ss Score
13.82
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
TCTACCTCCAAACACGAGCAAAATCCTCATTCTAATAAAAAGCTCAATAACTAAATGAGTAAACATAATATTCACATAAAGACGCCCTGAAGAACAACTTAAAAACTAAAAAGGGTCATCTGGAGTGGGCAGATAAAAGCAGCTGACGGACAAAAAAAAAAAAAACATTTAATCCCATACCAGCTTTCTACGCCTGGAAGTCGCAAAGGTAGAGCTCAAGAGAGGGGGAGCTAGCTCCCTGAAACCCCAGGAACCACAAAACTCCACTTGGACCACGAAATAATCATAAGCACGAAAAAACACAGACCAGACCAGTTGCCTTTTAAGCCCGCCACAAGATGGCGTGCCTTAACACCCTGAAGCAGGAAATCAAAACGCTAGAGAAGATCTTCCCGAAGAACCACGAGCGCTTTCAGATCCTCAATTCCAGCGTCGACGAACTGCTCTGCCGTTTTATCGATAAGAATGGAAAGCGGTACGATATTCACGCCAACATAACG
Seq A exon
GAAACGTATCCCTCATCGCCGCCAGTTTGGTTCGCCGAAAGCGAGGAGACGAGCGTCACAAATGCTGTTCAAATACTTAGCAATACGAATGGACGTGATAATCACGTGATCAATCAG
Seq C2 exon
GTGGGCATACTGCTGCGTGAGCTGTGCCGCCTTCACAACGTTCCACTGCCACCCGACATCGATAATTTGGCTCTGCCGCTGCAAACGCCGCCGCCATCCGCTTCCCCCCTTCGCTGCGAGCAGAGACCAGGTGGTGGTGGAGCGGGGGGCGGTGGCGGACCCCACGGCAACGAGGAGACCGATTCGGATCAGGAGGAGATCGAGGATCCCATCGGCGAGAGCGAACAGGAGAGCGAGGGCGATGAGGACTTGCCGCTGGAAATGGATGATGTACGCAGTACAAGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0023528-'8-7,'8-6,15-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.056 A=0.538 C2=0.802
Domain overlap (PFAM):
C1:
PF0577317=RWD=PU(51.0=96.3)
A:
PF0577317=RWD=FE(37.3=100)
C2:
PF0577317=RWD=PD(8.8=9.4)
Main Inclusion Isoform:
FBpp0070396
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0290017, FBpp0311475, FBpp0312228
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACACAGACCAGACCAGTTGC
R:
TGGCAGTGGAACGTTGTGAAG
Band lengths:
253-370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)