DmeEX6015523 @ dm6
Exon Skipping
Gene
FBgn0035879 | GAPcenA
Description
The gene GTPase activating protein and centrosome-associated is referred to in FlyBase by the symbol DmelGAPcenA (CG7112, FBgn0035879). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:8346561..8352279. Its molecular function is described by: GTPase activator activity; Rab GTPase binding. It is involved in the biological process described with: regulation of GTPase activity; intracellular protein transport; activation of GTPase activity; positive regulation of GTPase activity. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, during early pupal stages.
Coordinates
chr3L:8347775-8348689:+
Coord C1 exon
chr3L:8347775-8348053
Coord A exon
chr3L:8348256-8348439
Coord C2 exon
chr3L:8348502-8348689
Length
184 bp
Sequences
Splice sites
3' ss Seq
CATGTGTTTTTCACTTTCAGTTT
3' ss Score
11.47
5' ss Seq
TGTGTGAGT
5' ss Score
5.84
Exon sequences
Seq C1 exon
CTGCCAGTGGGGAGAAGTCAGCGCAACGTCTCCCGAGTCATCAGCAAAAGTCCCTGACCCTACCGCTCACGGGCTCCGGCGGGGGATCTGTCGATCCCGAGATGCGTTTCCCCTGCACCTTGTTCACGCCCAAAAGCGAGGAGACCCTCGACGATGCATCCAGCTCAAACAGAGTGGGTCATTCAGTGTTCTATGACTGCATAGACGCTAGCCCCGCCTGCGTGGAGGAAAAACAGGATGCCATGAAGCCGGAGAAGGGCGACACCACCGACGAGGAGG
Seq A exon
TTTCTGAAATCGATCAGGGCTGCACCATATTTTCCGGAGTCACCTACCTGGGCGCAGCCAACATTAATGCCCCAAAATCCGAGACGGAGGTTTATCGCATCATGGGCGAGCTAAATAGTGGCTCAAAGTCGGTGGGCCTGAAGATCACTGTGAGCATACCCAATTGCTCAGAAGGCCTGGTTGT
Seq C2 exon
CCTCCACGATGCCGAGAGCAATACTATTATTGCCACCTATGAGATATCCAGCATTATCTTGTACTATCGAGGACCAGTGGATACGGTGGAAAACGGATGCTTTGCATTCACTTGGCTTCACGGCGATGCATTGTTTCAGTGCCATGTGTTTCGGTGCCATATTCCCGAAGCGGTTAATCAAGTCAGCG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0035879-'1-4,'1-3,2-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.716 A=0.016 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0064018=PID=PU(39.3=77.4)
C2:
PF0064018=PID=FE(51.6=100)
Main Inclusion Isoform:
FBpp0112066
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0076332
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CACCTTGTTCACGCCCAAAAG
R:
CCGTATCCACTGGTCCTCGAT
Band lengths:
250-434
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)