Special

DmeEX6023473 @ dm6

Exon Skipping

Gene
FBgn0039427 | CG5447
Description
This gene is referred to in FlyBase by the symbol DmelCG5447 (FBgn0039427). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:26452534..26454585. Its molecular function is described by: protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: Golgi to plasma membrane protein transport; peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
Coordinates
chr3R:26452534-26453241:+
Coord C1 exon
chr3R:26452534-26452657
Coord A exon
chr3R:26452854-26453022
Coord C2 exon
chr3R:26453089-26453241
Length
169 bp
Sequences
Splice sites
3' ss Seq
GCCATTATCCGCCTTTTCAGCGA
3' ss Score
7.5
5' ss Seq
ATGGTGACT
5' ss Score
3.33
Exon sequences
Seq C1 exon
ATCTGGTAACACTTGGAGTTTGCAAACATTTATCTCTCGACCAATTTAAGGAATTTGAGGCAATTAGGGCATTCCTGTGAGCTTTTCCAGGCCAACTGCGATTACTTCAAGCCAAGACAAACAG
Seq A exon
CGACAACATGTCCCAAGGCGGTGGCACTACTCCAGCGGGCGGTAATCCCACAGCGCTCCAGGCGACCGGAGGGGGCGTGGTCTTCAGCAAGGTCTTCATCCAGCGCGATTACAGCGAGGGCACCTCCGTCAAGTTCCATACACGGCTGCCCGCTGAGCTGGAGGGCATG
Seq C2 exon
ATTGAAAGACACGTCTTCGAGGCCACCATCAATAGGCTAAACGAGTTCTACGCCGAGGCGGAGGAGGGATCCTGCGGCACCTATTGCGAGGGCTGCATTGGCTGCATCACGGCCTACTTGATCTATATGTGCTCCGAAACGCACTATGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0039427-'0-1,'0-0,1-1=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=0.278 C2=0.000
Domain overlap (PFAM):

C1:
NA
A:
PF102564=Erf4=PU(22.6=48.1)
C2:
PF102564=Erf4=FE(43.5=100)


Main Inclusion Isoform:
FBpp0303185


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0084384


Other Skipping Isoforms:
NA
Associated events
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGGTAACACTTGGAGTTTGCA
R:
ATCAAGTAGGCCGTGATGCAG
Band lengths:
245-414
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)