DreEX6026091 @ danRer10
Exon Skipping
Gene
ENSDARG00000062661 | abca4b
Description
ATP-binding cassette, sub-family A (ABC1), member 4b [Source:ZFIN;Acc:ZDB-GENE-050517-4]
Coordinates
chr2:15609760-15611228:+
Coord C1 exon
chr2:15609760-15609792
Coord A exon
chr2:15610935-15611040
Coord C2 exon
chr2:15611154-15611228
Length
106 bp
Sequences
Splice sites
3' ss Seq
AGGCATCTTTATTTCACCAGGTA
3' ss Score
6.56
5' ss Seq
GGGGTATGC
5' ss Score
6.16
Exon sequences
Seq C1 exon
CTTGAAGAGCAAATATTGGGTGAATGAGCAAAG
Seq A exon
GTATGGTGGAATCTCTGTTGGTGGAAGACTGCCGATTCTTGATGTGGACCCCGAGGAGATCCAAAACATTTTCTCTCAGCTTGGAAGAATGATGAATATCAGAGGG
Seq C2 exon
GGTCGCTATTCAAAGTCAGCCATGGATGAATTAGAAACTTTCCTGCACTACATGGAGAGCGAGTACAATGTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000062661-'40-38,'40-37,41-38=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=FE(2.9=100)
A:
PF126982=ABC2_membrane_3=FE(9.1=100)
C2:
PF126982=ABC2_membrane_3=FE(6.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTGAAGAGCAAATATTGGGTGA
R:
TAACATTGTACTCGCTCTCCATGT
Band lengths:
106-212
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000567; ELM sequence: MNVSGG; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]