DreEX6048011 @ danRer10
Exon Skipping
Gene
ENSDARG00000088825 | CDC42BPA
Description
CDC42 binding protein kinase alpha (DMPK-like) [Source:HGNC Symbol;Acc:HGNC:1737]
Coordinates
chr8:3824957-3827387:+
Coord C1 exon
chr8:3824957-3825154
Coord A exon
chr8:3826599-3826792
Coord C2 exon
chr8:3827252-3827387
Length
194 bp
Sequences
Splice sites
3' ss Seq
CTTCCTATGTGTGCACGCAGAAC
3' ss Score
8.31
5' ss Seq
CCGGTACAG
5' ss Score
5.65
Exon sequences
Seq C1 exon
GTGATCACGGATCTGGAGGAGCAGTTGACGCAGCTCACGCAAGAAAACGCGGAGCTGAACCGGCAGAACTTCTACCTGTCCAAACAGCTGGACGAGGCCACAGACGAGAACGAGGAGCGCCTGCAGCTCAAGCAGGACGTGGAGCGCCTCAGGAGAGAGGTGGCAGACCGAGAGATGCACCTCAACAACCAGAAACAG
Seq A exon
AACATCGAGACGCTGAAGACGACATGTACAATGCTGGAGGAGCAGGTTATGGAGCTGGAGACTCTGAATGATGAGCTGATGGAGAAGGAGAGGCAGTGGGAGAACTGGAGATCTGCTCTGGACGAGGAGAAAAACCAGGCCGAGCGCAGAGCCAGAGACCTGCAAAGACAGCTGGACAGCGAGAAGCAGAACCG
Seq C2 exon
ACTGCGTGCAGAACAGAGAAACTCTGAGTCTCGGCAGGCCGTGGAGCTGGCGGTGAAAGAGCACAAAGCTGAAATCCTGGTTCTGCAGCAGGCGCTCAAAGACCAGAAACTCAAGGCTGAGGGCCTTTCTGACACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000088825-'13-15,'13-14,14-15=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.606 A=0.723 C2=0.500
Domain overlap (PFAM):
C1:
PF079896=Microtub_assoc=PU(92.8=97.0)
A:
PF079896=Microtub_assoc=PD(4.3=4.6)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCGGCAGAACTTCTACCTGT
R:
TTTCTGGTCTTTGAGCGCCTG
Band lengths:
249-443
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]