HsaEX0015423 @ hg38
Exon Skipping
Gene
ENSG00000122966 | CIT
Description
citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985]
Coordinates
chr12:119730495-119735357:-
Coord C1 exon
chr12:119735160-119735357
Coord A exon
chr12:119734164-119734357
Coord C2 exon
chr12:119730495-119730630
Length
194 bp
Sequences
Splice sites
3' ss Seq
TCAGTGCTACTGATTTGCAGACG
3' ss Score
5.56
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
Exon sequences
Seq C1 exon
GTAATCACAGACCTGGAGGAGCAGCTAAACCAGCTGACCGAGGACAACGCTGAACTCAACAACCAAAACTTCTACTTGTCCAAACAACTCGATGAGGCTTCTGGCGCCAACGACGAGATTGTACAACTGCGAAGTGAAGTGGACCATCTCCGCCGGGAGATCACGGAACGAGAGATGCAGCTTACCAGCCAGAAGCAA
Seq A exon
ACGATGGAGGCTCTGAAGACCACGTGCACCATGCTGGAGGAACAGGTCATGGATTTGGAGGCCCTAAACGATGAGCTGCTAGAAAAAGAGCGGCAGTGGGAGGCCTGGAGGAGCGTCCTGGGTGATGAGAAATCCCAGTTTGAGTGTCGGGTTCGAGAGCTGCAGAGAATGCTGGACACCGAGAAACAGAGCAG
Seq C2 exon
GGCGAGAGCCGATCAGCGGATCACCGAGTCTCGCCAGGTGGTGGAGCTGGCAGTGAAGGAGCACAAGGCTGAGATTCTCGCTCTGCAGCAGGCTCTCAAAGAGCAGAAGCTGAAGGCCGAGAGCCTCTCTGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000122966_MULTIEX3-22/25=21-23
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.442 A=0.177 C2=0.174
Domain overlap (PFAM):
C1:
PF0149614=V_ATPase_I=PU(13.5=52.8),PF079267=TPR_MLP1_2=PU(11.9=27.8)
A:
PF0149614=V_ATPase_I=FE(40.5=100)
C2:
PF0149614=V_ATPase_I=PD(17.7=60.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAGGACAACGCTGAACTCAA
R:
CTGCAGAGCGAGAATCTCAGC
Band lengths:
248-442
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development