DreEX6083485 @ danRer10
Exon Skipping
Gene
ENSDARG00000019231 | spna2
Description
spectrin alpha 2 [Source:ZFIN;Acc:ZDB-GENE-051113-60]
Coordinates
chr21:13086922-13087396:+
Coord C1 exon
chr21:13086922-13086954
Coord A exon
chr21:13087085-13087120
Coord C2 exon
chr21:13087349-13087396
Length
36 bp
Sequences
Splice sites
3' ss Seq
TATTATATTTTATTTTGCAGGAT
3' ss Score
11
5' ss Seq
AAGGTAATA
5' ss Score
8.49
Exon sequences
Seq C1 exon
CAAGTAGAGGTGCTGGGCTCAGCTCCTGGCAAG
Seq A exon
GATGAAGCAGACTCCAAAGGTGCATCTCCATGGAAG
Seq C2 exon
TCTGTTCGCTTGGCTGTTCAAACAACGGCCAACTTTAATACTATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000019231-'31-37,'31-35,32-37=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=0.062
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=PD(6.7=54.5)
A:
PF0039314=6PGD=FE(9.5=100)
C2:
PF0039314=6PGD=FE(12.9=100),PF097304=BicD=PU(8.8=81.2),PF0043516=Spectrin=PU(32.4=68.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGTAGAGGTGCTGGGCTCAG
R:
CTTGATAGTATTAAAGTTGGCCGT
Band lengths:
80-116
Functional annotations
There are 1 annotated functions for this event
PMID: 9712874
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: classical fluorescence spectroscopy, cleavage reaction, glutathione s tranferase tag, western blot. ELM ID: ELMI001909; ELM sequence: DETDS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]