HsaEX0015434 @ hg38
Exon Skipping
Gene
ENSG00000122966 | CIT
Description
citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985]
Coordinates
chr12:119784960-119822973:-
Coord C1 exon
chr12:119822820-119822973
Coord A exon
chr12:119803206-119803389
Coord C2 exon
chr12:119784960-119785065
Length
184 bp
Sequences
Splice sites
3' ss Seq
TCTTGTTTTTCTTTAACCAGCTC
3' ss Score
7.57
5' ss Seq
TGAGTAAGT
5' ss Score
8.82
Exon sequences
Seq C1 exon
CGGTTTTTGAAATTTCCAGATGACCCCAAAGTGAGCAGTGACTTTCTTGATCTGATTCAAAGCTTGTTGTGCGGCCAGAAAGAGAGACTGAAGTTTGAAGGTCTTTGCTGCCATCCTTTCTTCTCTAAAATTGACTGGAACAACATTCGTAACT
Seq A exon
CTCCTCCCCCCTTCGTTCCCACCCTCAAGTCTGACGATGACACCTCCAATTTTGATGAACCAGAGAAGAATTCGTGGGTTTCATCCTCTCCGTGCCAGCTGAGCCCCTCAGGCTTCTCGGGTGAAGAACTGCCGTTTGTGGGGTTTTCGTACAGCAAGGCACTGGGGATTCTTGGTAGATCTGA
Seq C2 exon
GTCTGTTGTGTCGGGTCTGGACTCCCCTGCCAAGACTAGCTCCATGGAAAAGAAACTTCTCATCAAAAGCAAAGAGCTACAAGACTCTCAGGACAAGTGTCACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000122966_MULTIEX3-5/25=4-7
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.293 C2=0.477
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=PD(15.2=76.9)
A:
PF0043319=Pkinase_C=WD(100=75.8)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGATGACCCCAAAGTGAGC
R:
TGTGACACTTGTCCTGAGAGTCT
Band lengths:
243-427
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development