HsaEX6016770 @ hg38
Exon Skipping
Gene
ENSG00000091428 | RAPGEF4
Description
Rap guanine nucleotide exchange factor 4 [Source:HGNC Symbol;Acc:HGNC:16626]
Coordinates
chr2:172735841-172797613:+
Coord C1 exon
chr2:172735841-172736048
Coord A exon
chr2:172795025-172795167
Coord C2 exon
chr2:172797525-172797613
Length
143 bp
Sequences
Splice sites
3' ss Seq
TGCCTTTTCTCCCTATACAGACC
3' ss Score
10.42
5' ss Seq
CATGTAAGA
5' ss Score
5.58
Exon sequences
Seq C1 exon
GGGCGGGCCTGTCGCAGCCGCGCTGGTCGCCAGGCGTCCGGGAGGAGCGGGGTCCGCGCGGCGGACGAGGCGGGGGCGGAGGCGCAGGCAGAGCGAGCGCGGGAGGTCGCCGCAGCCAGGGACACCGCGCGCCGCCGCTCAACATGGTCGCTGCGCACGCTGCCCATTCTTCCTCCTCTGCCGAGTGGATCGCCTGCCTGGATAAAAG
Seq A exon
ACCACTGGAGCGATCCAGCGAAGATGTGGATATAATCTTCACTCGACTGAAAGAAGTTAAAGCTTTTGAGAAATTTCACCCAAATCTCCTTCATCAGATTTGCTTATGTGGTTATTATGAGAATCTGGAAAAGGGAATAACAT
Seq C2 exon
TATTTCGCCAGGGTGATATTGGAACAAACTGGTATGCTGTCCTGGCAGGGTCTTTGGATGTTAAAGTATCTGAGACCAGCAGTCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091428-'1-4,'1-3,5-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0002724=cNMP_binding=PU(20.0=18.4)
C2:
PF0002724=cNMP_binding=FE(31.5=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CCGCTCAACATGGTCGCTG
R:
TGGTGACTGCTGGTCTCAGAT
Band lengths:
162-305
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains