HsaEX6063294 @ hg19
Exon Skipping
Gene
ENSG00000197694 | SPTAN1
Description
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) [Source:HGNC Symbol;Acc:11273]
Coordinates
chr9:131347000-131349977:+
Coord C1 exon
chr9:131347000-131347122
Coord A exon
chr9:131348027-131348244
Coord C2 exon
chr9:131349885-131349977
Length
218 bp
Sequences
Splice sites
3' ss Seq
TTTCCCTACCCATCTTCCAGGCC
3' ss Score
10.73
5' ss Seq
GAGGTAACC
5' ss Score
8.55
Exon sequences
Seq C1 exon
GTAAGGATTTAATTGGGGTCCAGAATCTGCTAAAGAAACATCAAGCCTTACAAGCAGAAATTGCTGGACATGAACCACGCATCAAAGCAGTTACACAGAAGGGGAATGCCATGGTGGAGGAAG
Seq A exon
GCCATTTTGCTGCAGAGGATGTGAAGGCCAAGCTTCACGAGCTGAACCAAAAGTGGGAGGCACTGAAAGCCAAAGCTTCCCAGCGTCGGCAGGACCTGGAGGACTCTCTGCAGGCCCAGCAGTACTTTGCTGATGCTAACGAGGCTGAATCCTGGATGCGGGAGAAGGAACCCATTGTGGGCAGCACTGACTATGGCAAGGACGAAGACTCTGCTGAG
Seq C2 exon
GCTCTACTGAAGAAACACGAAGCTTTGATGTCAGATCTCAGTGCCTACGGCAGCAGCATCCAGGCTTTGCGAGAACAAGCACAGTCCTGCCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197694-'21-22,'21-21,22-22=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.476 A=0.425 C2=0.194
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=FE(39.0=100)
A:
PF0043516=Spectrin=PD(32.4=46.6),PF0043516=Spectrin=PU(42.9=49.3)
C2:
PF0043516=Spectrin=FE(35.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGGATTTAATTGGGGTCCAGA
R:
GGCAGGACTGTGCTTGTTCTC
Band lengths:
212-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)