HsaINT0132654 @ hg38
Intron Retention
Gene
ENSG00000110844 | PRPF40B
Description
pre-mRNA processing factor 40 homolog B [Source:HGNC Symbol;Acc:HGNC:25031]
Coordinates
chr12:49642580-49643016:+
Coord C1 exon
chr12:49642580-49642675
Coord A exon
chr12:49642676-49642926
Coord C2 exon
chr12:49642927-49643016
Length
251 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
3' ss Seq
CCTTCTTCCTCTGCCTCTAGCAG
3' ss Score
9.53
Exon sequences
Seq C1 exon
GTCCGTGAGCGTTTTGTGTGTGACTCAGCCTTTGAGCAGATCACCCTGGAGTCGGAGCGGATCCGGCTCTTCCGGGAGTTCCTACAGGTGCTGGAG
Seq A exon
GTGAGGCAGGCTTGTCCTCTGGATCTGCCTCAGGCCCTTGAACTCATTAGACCAGTTCAACAGAGACCTCAGTGGCCTCCCTCTTACCCTTAGGGCACTCCTGGCCAGCTAAGGAAGGGGAGGCCTGAGGATCCCTGGGATAGGCAGAAGGCTCTAGTCTGAGAAAGGGAGGCAAAGCCAGATTTTAGGAAGTAGGATCCTTCCTGGGGCTAAGTCTGGTGCTGTCCTCACCCTTCTTCCTCTGCCTCTAG
Seq C2 exon
CAGACTGAATGCCAGCACCTCCACACCAAAGGCCGAAAGCATGGCAGGAAAGGCAAGAAGCACCATCACAAGCGTTCCCACTCACCCTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000110844:ENST00000380281:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.933
Domain overlap (PFAM):
C1:
PF0184614=FF=PD(50.0=81.2)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTGAGCGTTTTGTGTGTGAC
R:
TGAGGGTGAGTGGGAACGC
Band lengths:
183-434
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development