Special

MmuEX0004882 @ mm9

Exon Skipping

Gene
ENSMUSG00000031543 | Ank1
Description
ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024]
Coordinates
chr8:24085316-24192763:+
Coord C1 exon
chr8:24085316-24085733
Coord A exon
chr8:24175424-24175525
Coord C2 exon
chr8:24192665-24192763
Length
102 bp
Sequences
Splice sites
3' ss Seq
GTTGTTTTCCGCCCCCACAGGCC
3' ss Score
10.36
5' ss Seq
CAGGTCAGT
5' ss Score
8.94
Exon sequences
Seq C1 exon
GGGCGGGCGCGGCGAGGGCGCGCGGCGAGCCCAGAGCCGGTGCGGGGCGCGGGCGAGCGAGCTCCGGCCGCGGCGGGAGGCGCCACCCCGGGGCTCGGCTAGCCGCGCGCCGGCCTCTCCTCGCCCTCCGCCCCGCGCCCCGGCCCCCGGGCGCCGCAGCCTTCGCCTCCGCCGGGGAGAAGCTCGCGCCCTGCGCAGCTGAAGGAGCCGGCTCTCCCCGGGAGGGTGTCGTCGCCGCCGGCTCGCAGAGGGCGCGGGCCCGGGAGGCGGGGACCGAGCGCCGCGACCCGCCATGGCTCAGGCGGCCAAACAGCTGAAGAAAATCAAAGACATCGAGGCGCAGGCCCTCCAGGAGCAGAAGGAGAAGGAGGAATCCAACAGGAAGCGGCGGAACCGCTCCCGTGACCGCAAGAAGAAG
Seq A exon
GCCGATGCTGCTACCAGCTTTCTGCGGGCGGCACGCTCGGGGAACCTGGACAAGGCTCTGGATCACCTGCGCAATGGAGTGGACATTAACACCTGTAACCAG
Seq C2 exon
AACGGGTTGAACGGCCTGCATCTGGCCTCCAAAGAAGGCCATGTGAAGATGGTGGTTGAACTTCTGCACAAAGAGATCATTCTAGAAACGACAACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000031543-'0-7,'0-6,4-7
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.762 A=0.156 C2=0.049
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF127962=Ank_2=PU(29.0=79.4)

							
C2:
PF127962=Ank_2=PU(29.0=81.8)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000113571





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000081050, ENSMUSP00000081051, ENSMUSP00000081051f2840A, ENSMUSP00000106313, ENSMUSP00000106316, ENSMUSP00000112850, ENSMUSP00000113495, ENSMUSP00000113531, ENSMUSP00000113656, ENSMUSP00000117966, ENSMUSP00000121785, ENSMUSP00000133322, ENSMUSP00000133901
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr8:41758036-41758137 
HIGH PSI
HsaEX0004110
(ANK1)
Human
(hg19)
chr8:41615554-41615655 
HIGH PSI
HsaEX0004110
(ANK1)
Rat
(rn6)
chr16:73820728-73820829 
HIGH PSI
RnoEX6055930
(Ank1)
Cow
(bosTau6)
chr27:36355419-36355520 
Chicken
(galGal4)
chr22:2635535-2635636 
HIGH PSI
GgaEX6024760
(chAnk1)
Chicken
(galGal3)
chr22:2686219-2686320 
HIGH PSI
GgaEX6024760
(Q90715_CHICK)
Zebrafish
(danRer10)
chr21:21053008-21053145 
Zebrafish
(danRer10)
chr5:68254682-68254783 
HIGH PSI
DreEX0000362
(ANK1 (1 of 2))
Fruitfly
(dm6)
chr3L:7710868-7710969 
HIGH PSI
DmeEX6015357
(Ank2)
Fruitfly
(dm6)
chr4:123785-123892 
HIGH PSI
DmeEX6024763
(Ank)




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCTGAAGGAGCCGGCTCTC

				
R: 
TTCTTTGGAGGCCAGATGCAG

				
Band lengths: 
257-359

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"