DmeEX6024763 @ dm6

Exon Skipping

Gene

Description

The gene Ankyrin is referred to in FlyBase by the symbol DmelAnk (CG1651, FBgn0011747). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 4:115074..129849. Its molecular function is described by: cytoskeletal anchor activity; spectrin binding; ion channel binding. It is involved in the biological process described with: signal transduction; protein localization to plasma membrane. 10 alleles are reported. The phenotype of these alleles manifest in: ovariole. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period.

Coordinates

chr4:122309-129442:-

Coord C1 exon

chr4:129322-129442

Coord A exon

chr4:123785-123892

Coord C2 exon

chr4:122309-123422

Length

108 bp

Sequences

Splice sites

3' ss Seq

ATTATTAATTACATTTTCAGAAT

3' ss Score

6.43

5' ss Seq

GCAGTAAGT

5' ss Score

9.07

Exon sequences

Seq C1 exon

GCCATTATATTAAATTATGACGCTTGGTGATGTACGAGTTGAGAACAAAATACAAACAAGAAGTGAAACCTGTGCTATCAATGGAATGGCTTTAGACAACAAGAATGGAATCATAAAACAG

Seq A exon

AATGACGCAACCATTTCGTTCTTACGTGCTGCTCGCAGCGGAGACATTAAAAAGGTGATGGATTTTTTGGACTGTGGAGAAATATCAGACATAAATAGCTGCAATGCA

Seq C2 exon

AACGGTCTTAATGCACTTCATTTAGCTGCAAAGGACGGATATGTGGACATATGCTGCGAGTTGCTAAGAAGGGGCATAAAGATCGATAATGCCACAAAAAAGGGAAACACAGCCTTGCACATTGCGTCTTTGGCGGGGCAGCATGATGTCATCAATCAGCTAATTTTATATAATGCTAATGTGAACGTGCAGTCTCTTAATGGTTTCACCCCGCTTTATATGGCAGCACAAGAAAACCACGACAATTGTTGTCGAACCCTATTGGCCAATGGGGCAAATCCGTCATTATCTACAGAAGATGGCTTCACACCACTTGCGGTAGCAATGCAGCAGGGACACGACAAAATTGTAGCTGTCTTACTTGAAAATGACGTGCGTGGGAAGGTTCGCCTACCAGCTCTTCATATTGCTGCGAAAAAAAATGATGTAAATGCAGCTAAGTTATTACTTCAACATGATCCCAATGCTGACATCGTTTCCAAATCAGGATTCACCCCTTT

VastDB Features

Vast-tools module Information

Secondary ID

FBgn0011747-'8-6,'8-4,12-6=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

Alternative protein isoforms (Ref)

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.000 C2=0.003

Domain overlap (PFAM):

C1:

NO

A:

PF127962=Ank_2=PU(30.5=80.6)

C2:

PF127962=Ank_2=PD(67.4=17.2),PF0002325=Ank=WD(100=8.9),PF0002325=Ank=WD(100=7.3),PF127962=Ank_2=WD(100=25.5),PF136371=Ank_4=WD(100=14.5),PF127962=Ank_2=WD(100=19.4),PF0002325=Ank=PU(36.4=3.2)

Main Inclusion Isoform:

FBpp0088238