DmeEX6015357 @ dm6
Exon Skipping
Gene
FBgn0261788 | Ank2
Description
The gene Ankyrin 2 is referred to in FlyBase by the symbol DmelAnk2 (CG42734, FBgn0261788). It is a protein_coding_gene from Dmel. It has 21 annotated transcripts and 21 polypeptides (20 unique). Gene sequence location is 3L:7655389..7718395. Its molecular function is unknown. It is involved in the biological process described with 9 unique terms, many of which group under: nervous system process; system process; positive regulation of multicellular organismal process; regulation of trans-synaptic signaling; organelle organization. 41 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; cell junction; synapse; cell component; dendritic tree. The phenotypic classes of alleles include: stress response defective; increased mortality; phenotype; neuroanatomy defective.
Coordinates
chr3L:7710349-7713650:-
Coord C1 exon
chr3L:7713138-7713650
Coord A exon
chr3L:7710868-7710969
Coord C2 exon
chr3L:7710349-7710801
Length
102 bp
Sequences
Splice sites
3' ss Seq
TATGAAACTTTATTTTCTAGGGC
3' ss Score
8.94
5' ss Seq
GCGGTAAGC
5' ss Score
8.99
Exon sequences
Seq C1 exon
TGAACATCGAAGAAAACGGCAGCAAAACCGAAAACTGCTCCTCGAGAACCGTGAACTTAATAAGGGACTGTGTGAGAGCAGCCAGGAGTCCAATCAGACACATACACACACACAAAGACATTTACACCCATACACTGACACTGACACGCACACAACCGAATCGGTGGCCTGTACGAACACACCCTCTCGCACACTCATGCACTCGTGTACATATAGCTTACATAAAGTCTAAGGAAAAATCGATAGGAGTGCATTAATAATTCAGCGAAAACGAAGAGCATAAGGTCTCGAGCAAAAATCTTCAAGTAGTGCGAGTTTTCCGCCTCTGCTAACGGTGAAGAAAAGTTCCAGGCCTCGTGAAAAAATATGACTAATCTGCAGTGACGACATACGCGCCGCTTACACAATTTCTCTACACCAATTAATCGCTGAAATCAATTCAAGACGGGCATTTTACCATTGGCAATTGTGAAAAAATGGTCACCGAAAATGGAGCACAG
Seq A exon
GGCGATGGAAACACTTCCTTCCTGCGTGCCGCTCGCGCCGGAAATCTGGAGCGAGTGCTCGAGCATTTGAAGAACAACATTGACATTAACACCAGCAATGCG
Seq C2 exon
AATGGCTTGAATGCCCTGCACCTGGCCTCCAAGGATGGCCACATCCACGTCGTCTCGGAACTCCTTCGTAGGGGCGCGATTGTGGATAGTGCCACCAAAAAGGGAAACACTGCCCTCCACATCGCCTCATTGGCTGGACAGGAGGAGGTGGTGAAGCTACTGCTGGAGCACAATGCCTCCGTAAATGTGCAATCCCAGAATGGATTCACTCCACTCTACATGGCTGCCCAGGAGAACCACGATGCTGTGGTGCGTCTCCTTTTGTCCAACGGAGCCAACCAGAGTCTGGCCACCGAGGATGGCTTCACCCCACTGGCGGTGGCCATGCAGCAGGGTCATGACAAAGTCGTTGCTGTCCTCCTCGAGAGTGATACTCGTGGAAAGGTCAGGCTTCCTGCGCTGCACATTGCCGCCAAAAAGGACGACGTCAAGGCAGCGACTCTGCTTCTCGAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261788-'2-5,'2-4,3-5=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.750 A=0.287 C2=0.064
Domain overlap (PFAM):
C1:
PF138571=Ank_5=PU(8.3=50.0)
A:
PF127962=Ank_2=PU(28.7=79.4)
C2:
PF127962=Ank_2=PD(41.9=20.5),PF127962=Ank_2=WD(100=47.0),PF0002325=Ank=WD(100=18.5),PF127962=Ank_2=PU(18.3=11.3)
Main Inclusion Isoform:
FBpp0292244
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0292230, FBpp0292231, FBpp0292232, FBpp0292233, FBpp0292234, FBpp0292236, FBpp0292237, FBpp0292238, FBpp0292239, FBpp0292240, FBpp0292241, FBpp0292242, FBpp0292243, FBpp0306185, FBpp0306186, FBpp0306187, FBpp0310628, FBpp0310629, FBpp0310630
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GGTCACCGAAAATGGAGCACA
R:
GCAGCCATGTAGAGTGGAGTG
Band lengths:
249-351
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)