Special

MmuEX0004918 @ mm9

Exon Skipping

Gene
ENSMUSG00000069601 | Ank3
Description
ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]
Coordinates
chr10:69355070-69395244:+
Coord C1 exon
chr10:69355070-69355267
Coord A exon
chr10:69356193-69356291
Coord C2 exon
chr10:69395142-69395244
Length
99 bp
Sequences
Splice sites
3' ss Seq
GCCCTTGGGATCTCTTGCAGAGC
3' ss Score
8.21
5' ss Seq
AAGGTACAT
5' ss Score
7.87
Exon sequences
Seq C1 exon
AATGGCTATACACCACTGCACATCGCGGCCAAGAAGAACCAGATGGACATAGCCACGTCCCTGCTGGAGTACGGTGCTGATGCAAACGCGGTTACCCGGCAAGGGATTGCGTCCGTCCATCTTGCGGCACAGGAAGGGCACGTGGACATGGTGTCGCTGCTCCTGAGTAGAAACGCGAATGTCAACCTGAGCAATAAG
Seq A exon
AGCGGTCTCACCCCACTCCACCTGGCTGCTCAAGAAGACCGAGTGAATGTGGCCGAGGTCCTTGTCAACCAGGGGGCCCATGTGGATGCTCAGACAAAG
Seq C2 exon
CCTCCGCTCCTTCAGTTCGGATAGGTCCTACACCTTGAACAGAAGCTCCTACGCAAGGGACAGCATGATGATAGAGGAACTTCTGGTACCATCCAAAGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000069601_MULTIEX1-17/25=16-25
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.015 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127962=Ank_2=PD(33.3=47.0),PF127962=Ank_2=PU(29.0=40.9)

							
A:
PF127962=Ank_2=FE(34.4=100)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000090090f5603A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000090089





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000061698, ENSMUSP00000090087, ENSMUSP00000090088, ENSMUSP00000090090, ENSMUSP00000090090f5390A, ENSMUSP00000090090f5391A, ENSMUSP00000090090f5392A, ENSMUSP00000090090f5393A, ENSMUSP00000090090f5394A, ENSMUSP00000090090f6290A, ENSMUSP00000090090f6291A
          









    
Other Skipping Isoforms:
NA
  



Associated events







Conservation


Human
(hg38)
chr10:60181329-60181427 
HIGH PSI
HsaEX1003659
(ANK3)
Human
(hg19)
chr10:61941087-61941185 
Rat
(rn6)
chr20:20348774-20348872 
HIGH PSI
RnoEX6062478
(Ank3)
Cow
(bosTau6)
chr28:15967605-15967703 
HIGH PSI
BtaEX6105143
(ANK3)
Chicken
(galGal4)
chr6:8422370-8422468 
HIGH PSI
GgaEX6039834
(chAnk3)
Chicken
(galGal3)
chr6:10083280-10083378 
HIGH PSI
GgaEX6039834
(Q90717_CHICK)
Zebrafish
(danRer10)
chr12:7686272-7686370 
HIGH PSI
DreEX6067857
(ank3b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GGATTGCGTCCGTCCATCTTG

				
R: 
ATCATCATGCTGTCCCTTGCG

				
Band lengths: 
167-266

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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