Special

MmuINT0015156 @ mm9

Intron Retention

Gene
ENSMUSG00000069601 | Ank3
Description
ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]
Coordinates
chr10:69366946-69367258:+
Coord C1 exon
chr10:69366946-69367018
Coord A exon
chr10:69367019-69367195
Coord C2 exon
chr10:69367196-69367258
Length
177 bp
Sequences
Splice sites
5' ss Seq
AAGGTATGG
5' ss Score
9.26
3' ss Seq
TTATCACTTAAATCATGCAGTAA
3' ss Score
2.31
Exon sequences
Seq C1 exon
ACCATCACGGAGAAGCACAAAATGAATGTCCCAGAAACGATGAATGAAGTCCTCGATATGTCAGACGATGAAG
Seq A exon
GTATGGCAGTGTCCTCGAGGGGTTGCCATGGTGATGAGTGACCCTGTCTCTGTTGCTTCCTGAAGAAAGTCTGTCACAAACGTGTTTTGGGCGAGGGGTGGAATGTTTAGATGTTGGTAGTTGTGTCATGGGAGATGAGTATTTTCATACACTCTTATTATCACTTAAATCATGCAG
Seq C2 exon
TAAGGAAAGCCAGCGCCCCCGAAAAGCTCAGTGATGGGGAATATATCTCAGACGGTGAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000069601-Ank3:NM_146005:22
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.945 A=NA C2=0.793
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NA

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000090090f5603A





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000090088, ENSMUSP00000090090, ENSMUSP00000090090f5390A, ENSMUSP00000090090f5391A, ENSMUSP00000090090f5392A, ENSMUSP00000090090f5393A, ENSMUSP00000090090f5394A, ENSMUSP00000090090f6290A, ENSMUSP00000090090f6291A
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr10:60166654-60166823 
ALTERNATIVE
HsaINT0008158
(ANK3)
Human
(hg19)
chr10:61926412-61926581 
ALTERNATIVE
HsaINT0008158
(ANK3)
Rat
(rn6)
chr20:20358578-20358747 
LOW PSI
RnoINT0017408
(Ank3)
Cow
(bosTau6)
chr28:15990972-15991134 
Chicken
(galGal4)
chr6:8438373-8438574 
ALTERNATIVE
GgaINT0041359
(chAnk3)
Chicken
(galGal3)
chr6:10099283-10099484 
LOW PSI
GgaINT0041359
(Q90717_CHICK)
Zebrafish
(danRer10)
chr12:7675981-7676293 
LOW PSI
DreINT0029732
(ank3a)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACCATCACGGAGAAGCACAAA

				
R: 
TCACCGTCTGAGATATATTCCCCA

				
Band lengths: 
131-308

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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