MmuEX0028276 @ mm10
Exon Skipping
Gene
ENSMUSG00000039842 | Mcph1
Description
microcephaly, primary autosomal recessive 1 [Source:MGI Symbol;Acc:MGI:2443308]
Coordinates
chr8:18688982-18803189:+
Coord C1 exon
chr8:18688982-18689059
Coord A exon
chr8:18788239-18788476
Coord C2 exon
chr8:18801406-18803189
Length
238 bp
Sequences
Splice sites
3' ss Seq
TTCCTTTCATCTGCCCACAGATC
3' ss Score
11.88
5' ss Seq
TAGGTAGGA
5' ss Score
7
Exon sequences
Seq C1 exon
GTACTGTTGTCTTTAGAGTTGGGCCACTGGATTTCTGAGGAGCCTTTTGAACTCTCTGAAACCTTCCCTGCAGCTCCG
Seq A exon
ATCTGCCGACTTGAACGCCATTTATCTACCCAGCAATACCAAGGAACCCTCTTTGCTAATCAGCCGAAGATGTTCATAGCGCCAGCCAGCAGCCCTCCCAGAGCCAAACTGTGTGAACTGGTACTCCTGTGTGGTGGCCAAGTCAGCCCAGCCCCTCAGCTGGCCAGCCTCATCATTGGTCCCTACAAGGGCAAGAAGAAAGCAAGGATCCAGTACCTGTCAGAGAAATGGGTCTTAG
Seq C2 exon
ATTCCATCACCCAACACAAGATCTGTGACTTTAACAACTACCAACTGCTACAGTGAGACATCTACAATGAGGCTGCTATCCTCAACACTCAAGAAGAACAACTCTGGAGAAAAGGAACCAGCAGACACCTTAGGGCTTGAAGTCACATGTCACTTTGTGTGCTATGGTTTTTATCTTCAGAGGGTATGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTAGGTGTCTAGAGATTAAATCCAAGGCTTGCTAAGTAAGCACTGTACTGTGGAACTACATCTCCAGCTTTTATCCTTAAAACTCTTTATGTAACTTATTCATGACTCATTGTATTTCAGAGAAGTCTTGACCAGCACCAGTTGGGTACTTTATACAATACTAATAATGATCATGATGGAAAGGTCACAGAACCTTTGTCCTTGAGATACTTGTTCCCAATTATAGAATGGAAGTTGATTTAAATTGCTGTAGTCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039842_MULTIEX1-12/12=11-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0053321=BRCT=PD(6.0=15.4)
A:
PF0053321=BRCT=PU(95.5=80.0)
C2:
PF0053321=BRCT=PD(3.0=10.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCACTGGATTTCTGAGGAGC
R:
ACACACACACACACACACACA
Band lengths:
292-530
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types