MmuEX6056574 @ mm9
Exon Skipping
Gene
ENSMUSG00000023033 | Scn8a
Description
sodium channel, voltage-gated, type VIII, alpha [Source:MGI Symbol;Acc:MGI:103169]
Coordinates
chr15:100863909-100876360:+
Coord C1 exon
chr15:100863909-100864013
Coord A exon
chr15:100865866-100866136
Coord C2 exon
chr15:100869972-100876360
Length
271 bp
Sequences
Splice sites
3' ss Seq
CTTCTGTCTTTCCTCTGCAGAAC
3' ss Score
12.8
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
TTTGGAGGTCAGGACATCTTCATGACAGAGGAACAGAAGAAGTACTACAACGCCATGAAGAAGCTAGGCTCCAAGAAGCCACAGAAGCCCATCCCCCGACCTTTG
Seq A exon
AACAAAATCCAAGGGATTGTCTTTGATTTCGTCACGCAACAAGCCTTCGACATCGTGATCATGATGCTTATCTGCCTTAACATGGTGACCATGATGGTGGAGACAGACACACAGAGCAAGCAGATGGAGAACATTCTCTACTGGATTAATCTGGTCTTCGTCATCTTCTTCACCTGCGAGTGTGTGCTCAAAATGTTTGCCTTGAGACACTACTATTTCACCATTGGCTGGAACATCTTTGACTTTGTGGTGGTCATTCTCTCCATTGTGG
Seq C2 exon
GAATGTTCCTGGCTGATATCATTGAGAAGTACTTCGTCTCCCCGACCCTATTCCGCGTCATCCGATTGGCCCGCATCGGGCGCATCTTGCGTCTGATCAAGGGCGCCAAAGGGATCCGCACCCTGCTCTTTGCCTTAATGATGTCGCTGCCCGCCCTGTTCAACATCGGCCTCCTGCTCTTCCTGGTCATGTTCATCTTCTCCATCTTTGGGATGTCCAACTTCGCGTACGTGAAGCACGAGGCCGGCATTGATGACATGTTCAACTTCGAGACGTTTGGCAACAGCATGATCTGCCTGTTCCAGATCACGACCTCTGCTGGTTGGGATGGCTTACTGCTGCCAATCCTGAACCGCCCCCCTGACTGCAGCTTGGACAAGGAGCACCCAGGAAGTGGCTTCAAAGGGGACTGCGGGAACCCCTCCGTGGGCATCTTCTTCTTCGTCAGCTACATCATCATCTCCTTTCTGATCGTGGTAAACATGTACATTGCCATCATC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000023033-'30-29,'30-28,31-29=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.160
Domain overlap (PFAM):
C1:
NO
A:
PF0052026=Ion_trans=PU(20.5=47.3)
C2:
PF0052026=Ion_trans=PD(79.0=43.3),PF0061222=IQ=WD(100=5.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACGCCATGAAGAAGCTAGGC
R:
CTTCACGTACGCGAAGTTGGA
Band lengths:
293-564
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: