MmuEX6056590 @ mm9
Exon Skipping
Gene
ENSMUSG00000023033 | Scn8a
Description
sodium channel, voltage-gated, type VIII, alpha [Source:MGI Symbol;Acc:MGI:103169]
Coordinates
chr15:100800635-100803391:+
Coord C1 exon
chr15:100800635-100800698
Coord A exon
chr15:100801951-100802092
Coord C2 exon
chr15:100803185-100803391
Length
142 bp
Sequences
Splice sites
3' ss Seq
GTGTCCCTTTCCTTCTTCAGGCA
3' ss Score
11.24
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
Exon sequences
Seq C1 exon
CAAACTTTTACATGGTCCCTGGCATGCTAGAACCCTTGCTCTGCGGGAACAGCTCTGACGCCGG
Seq A exon
GCAATGCCCAGAGGGGTTCCAGTGCATGAAAGCAGGAAGAAATCCCAACTACGGCTACACCAGCTTCGACACCTTCAGCTGGGCCTTCCTGGCACTGTTCCGCCTCATGACTCAGGACTACTGGGAGAACTTATACCAGCTG
Seq C2 exon
ACCTTACGAGCGGCTGGGAAAACGTACATGATCTTCTTTGTCTTGGTGATCTTCGTGGGTTCTTTCTATTTGGTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTACGAAGAGCAGAACCAGGCAACACTGGAGGAGGCAGAGCAGAAAGAGGCAGAGTTCAAGGCGATGCTGGAGCAGCTCAAGAAGCAGCAGGAGGAGGCGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000023033-'7-8,'7-7,8-8=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.068
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(8.4=100),PF057587=Ycf1=FE(7.7=100)
A:
PF0052026=Ion_trans=FE(18.7=100),PF057587=Ycf1=FE(17.2=100)
C2:
PF0052026=Ion_trans=PD(12.4=44.9),PF057587=Ycf1=FE(24.9=100),PF0310514=SPX=PU(19.9=55.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGGCATGCTAGAACCCTTG
R:
CTCCTCCTGCTGCTTCTTGAG
Band lengths:
248-390
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: