BtaEX0031585 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000021339 | SCN8A
Description
sodium channel, voltage gated, type VIII alpha subunit [Source:HGNC Symbol;Acc:HGNC:10596]
Coordinates
chr5:28281584-28284602:-
Coord C1 exon
chr5:28284539-28284602
Coord A exon
chr5:28283310-28283451
Coord C2 exon
chr5:28281584-28281790
Length
142 bp
Sequences
Splice sites
3' ss Seq
GCTTCCTTTTCTTTCCTCAGGCA
3' ss Score
10.34
5' ss Seq
TTAGTAAGT
5' ss Score
7.79
Exon sequences
Seq C1 exon
CAAATTTCTACATAGTTCCTGGTATGCTGGAACCTTTGCTCTGTGGGAACAGTTCTGATGCTGG
Seq A exon
GCAATGTCCAGAGGGATACCAGTGTATGAAGGCAGGAAGGAACCCCAACTATGGTTACACGAGCTTTGACACTTTCAGCTGGGCCTTCTTGGCATTATTTCGCCTTATGACCCAGGACTACTGGGAAAACTTGTATCAATTA
Seq C2 exon
ACCTTACGAGCAGCTGGGAAAACGTACATGATCTTCTTCGTCTTGGTCATCTTTGTGGGTTCTTTCTATCTGGTGAACTTGATCCTGGCTGTGGTGGCCATGGCTTATGAAGAGCAGAATCAGGCAACACTGGAGGAAGCAGAGCAGAAAGAGGCTGAATTCAAAGCAATGTTAGAGCAACTTAAGAAGCAACAGGAAGAAGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000021339-'7-11,'7-10,8-11
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.116
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(8.4=100)
A:
PF0052026=Ion_trans=FE(18.7=100)
C2:
PF0052026=Ion_trans=PD(12.4=44.9),PF0310514=SPX=PU(19.6=55.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTGGAACCTTTGCTCTGTG
R:
TGTGCTTCTTCCTGTTGCTTCT
Band lengths:
246-388
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development