MmuEX6073828 @ mm10
Exon Skipping
Gene
ENSMUSG00000028125 | Abca4
Description
ATP-binding cassette, sub-family A (ABC1), member 4 [Source:MGI Symbol;Acc:MGI:109424]
Coordinates
chr3:122052902-122055457:+
Coord C1 exon
chr3:122052902-122052995
Coord A exon
chr3:122054192-122054333
Coord C2 exon
chr3:122055318-122055457
Length
142 bp
Sequences
Splice sites
3' ss Seq
TTTTCATTTCCTGTCTTAAGGCC
3' ss Score
8.19
5' ss Seq
CATGTAAGT
5' ss Score
8.31
Exon sequences
Seq C1 exon
ATTCGCTTTGTAGTGGAACTCGTGTGGCCTTTGTCTTTGTTTTTGGTGTTAATCTGGCTGAGGAATGCCAACCCACTCTATAGTCAGCATGAAT
Seq A exon
GCCATTTTCCCAACAAGGCGATGCCTTCAGCAGGACTGTTACCGTGGCTCCAGGGGATTTTCTGCAATATGAACAACCCTTGTTTTCAAAACCCCACCCCTGGAGAGTCTCCTGGAACTGTCTCAAACTATAACAACTCCAT
Seq C2 exon
CTTGGCAAGAGTATATCGAGATTTTCAAGAACTCTTCATGGACACCCCGGAGGTCCAGCACCTTGGCCAGGTTTGGGCCGAGCTCCGCACCTTGTCGCAGTTCATGGACACCCTGAGGACTCACCCTGAGAGATTTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000028125-'7-15,'7-4,8-15=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.167 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTCGCTTTGTAGTGGAACTCGT
R:
CTGCAAATCTCTCAGGGTGAGT
Band lengths:
234-376
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000561; ELM sequence: YNNSIL; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types