Special

MmuINT0054173 @ mm9

Intron Retention

Gene
ENSMUSG00000029757 | Dync1i1
Description
dynein cytoplasmic 1 intermediate chain 1 [Source:MGI Symbol;Acc:MGI:107743]
Coordinates
chr6:5717030-5719791:+
Coord C1 exon
chr6:5717030-5717144
Coord A exon
chr6:5717145-5719649
Coord C2 exon
chr6:5719650-5719791
Length
2505 bp
Sequences
Splice sites
5' ss Seq
TAGGTACTT
5' ss Score
5.6
3' ss Seq
CTGACACTGCTCTTCCCCAGTGC
3' ss Score
7.42
Exon sequences
Seq C1 exon
GCAGATATGCAGCAAAAGAAAGAGCCCGTTCAAGATGACTCCGATCTGGATCGCAAACGACGGGAGACAGAAGCTTTGCTTCAGAGCATTGGCATATCACCGGAGCCCCCTCTAG
Seq A exon
GTACTTCCCCAAGCTTGCGTTGCTACTCCTCTTGTGTAAATATACCATGTCCAGCGTTACTGTGCTCTTAAGTGTTAGCTTTATTGTTGTTTTCTATGCTTAAGAAAGAAAGCTAGGGCTTACTGTTCTAGTTGCATGTACTTTGTAGAAGTGAGAGGGCTGGAAGGACATGCGAATGTTGCTTAGTCATCAGCCTTTGCTAATGATACACTGGCTGATTATATGCTCATAGCTTCCCCTTGTGTCACTACCAGATTCGTTTATATTGTTAAGAGAGTATGTAGAAGACATCTTGGGATTTTTTTTAAGCATCAAATTGTTCTTTGCTTCTGTGGGTGAATCCCAACCTCGCTTTGCCTATTCAGACAATGCTAATCTGGTTATAAATACTGGGAACACTACAGACATAGAATTATCCCATGATGAAAATAGAGTTTTCAGTGGGAAATTTATTTGGCTCGTGTGTACCTTGATTTCATTGCTCGCTGACATTTCCACGGCAGCATTTCCTCCTCCTCCAACTCATTCACTTCTAGTTGATTGTCTGTGAAGTCTTTTGTCATGGAGGTCTGGGTACAGATTAATTTGTATTTGATTTGTTAAAGGTAGTTTGCATGAGCTTATTCTGTCACTATCTTGTGTATCTTTCATGGGTTCTTTTCTTTTTCTTTTCTTTATCTTCCATACATCTAAAAATAACCCAAAGGTGTCTGCAAAACTACATAATATCCACTACATTCAAAATAAAACCATTTAAATTCTGCACAGGAATAAATACTATATCAGGGCCATTTAAAATGTTTCATCTTTTAAATTCCATTCTTGGATTCCATATTAAAATAGAATCCCTTTTATTCTCATAGATACTTAAATTAAGAAAAAAAATTACCTATGTGAAATAATCAATATAAATAAGAAAAAGAATATATCCAACTTAAAATTAAGTATTGGTAAATATGATTTAGTGCATAAACATAAAACTAAAATCCTACTAAAAAGCATAACAGTGTATCTCAATTGCATGTAAAAAGCATATGCCTATTGCTATAATGAGCCCTCATAAAATTAGATTTTATTTAACTTCTTATTATGCAAGGTGTAATCTATAGAGGATTTGGCTGGTGGATCTTCTTTGAGAAGTTGGCAAACCTCTTTGTACTTAGCTGACATGTGATGTAAATTAGACATCTATCGATCAATTATATTTTGGCTTCAAAATAGTCTGAAATGTTGTAGTTGCTATGTCAATACTGGTTAAACCCAGTAGAAGTATATGTGATCATCCCTTACCCTGAAAAGAGCTGGTGATTAAATTTTAAAAACAAAATACTTGAGTATCCCCAGTCTGCAACTACCTTCTCAACTACACATGAATCCTTTCCAAAAGGCCCATTTTTCATCTCTCTTCCCAGCTTTCCCTCTACCCTAACACGAAGGGTAATCAGATAATTAATTGAAGAGCCACAAGGAAATGCCCAGTTCCTTGGCAATTCTGTCTTTGTGGTACAGAATTTGAGGGCAGAGAGAATAAAAACCTGTTAAACCTTATACCCTATTAAATAAATACAAGGGACTCTATGTTCATGCAGCCTCTTTCTGCACATGGCTTCCTTGGCATGTGTGATGAGTCCCCTAAATTGCCTGGCCTGGAGCCATTATGCCTCTTGGGTACAGCAAGTGGCTGATGGACATTTGGCTTAGATATGGAGGTTGCAGAAAGAAAACACATCTCTGTCTGTTTTGTTTTGTTTTGTTTTCCCTTGGTTATCCTTGCTCAGATTGTCAGCTGACCTGGATCTCTGAGCATCTTTCTTTCTCCCACTCTCATGGTGGCAGTTCACTTCTTGTCTTGTGTCAGCATCTACAAGAGCTGCTAGAGACAAAGAAAACAAGTCCCAAGTGAAGTAGAATGTAGGGTTGGGTGAAACCATTCATTAAATGTAAAAATAAAGCAGGCTGGCATTTTCCTTTGTTTTGAAAGAGATTGTTTTAATTACCAGGCTCAACATTTACCCTTCCCCTCTGTCATCCGATCTTAGCACAAAGTTGTTCATCCACCATGAACCCTTACATTTCTCTCCAAATTAGACAATCAATAGATCTCTCACCACTCTTGAGCATTTAATTGTTTAGGCTCTTCCAATTTCATAATGTTTAAAGTTTTATAGACACCTCATCTTTTAAATAGGTCACGTCTATACTAACAAAATAAAGTGAAGAATTAGAATGAGCTAGATAGTTCCTACCGAAAAAATGTAGGGTGAACTATCTGGATAGCTATGTGGTTCTCCGCTTTACTTCGTTAGGTGGACATGACCTTGGACTCCCTAAGTTAATTCTGTCTAAATTCATTTCAGACTCTCATTTTCCAAAATATGAAAAATTCACTTGACTTTCTTCCTTTTCTTTCCTTTTTTTTTAATCCCATTTCTATCTCTCCTGGCCATACAACCACTTTAATTTGGGCCCGTTTGTTTTGATTTGTCTGACACTGCTCTTCCCCAG
Seq C2 exon
TGCAGCCGTTGCATTTTTTAACATGGGATACCTGTTATTTTCATTATTTAGTCCCAACCCCTATGTCTCCCTCTTCGAAATCAGTGAGCACTCCCAGTGATGCTGGAAGCCAAGACTCGGGCGATCTGGGGCCATTAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029757-Dync1i1:NM_001191023:3
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.962 A=NA C2=0.735
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF044177=DUF501=FE(7.4=100),PF0099215=Troponin=FE(8.7=100)

							
A:
NA

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000111217





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000111216, ENSMUSP00000111218, ENSMUSP00000111221, ENSMUSP00000121787
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr7:95810507-95813246 
ALTERNATIVE
HsaINT1012032
(DYNC1I1)
Human
(hg19)
chr7:95439819-95442507 
HsaINT0053153
(DYNC1I1)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr4:12998431-13001166 
LOW PSI
BtaINT0053550
(DYNC1I1)
Chicken
(galGal4)
chr2:24088007-24090714 
LOW PSI
GgaINT0091987
(DYNC1I1)
Chicken
(galGal3)
chr2:23920729-23923385 
GgaINT0091987
(DYNC1I1)
Zebrafish
(danRer10)
chr6:3774716-3778065 
LOW PSI
DreINT0060572
(dync1i2b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"