Special

FBgn0012051 @ dm6

Biotype
protein_coding
Gene Symbol
CalpA
Description
The gene Calpain-A is referred to in FlyBase by the symbol DmelCalpA (CG7563, FBgn0012051). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2R:19425113..19430564. Its molecular function is described by: calcium ion binding; calcium-dependent cysteine-type endopeptidase activity. It is involved in the biological process described with 9 unique terms, many of which group under: multicellular organismal process; metabolic process; multicellular organism development; protein metabolic process; organonitrogen compound metabolic process. 22 alleles are reported. The phenotype of these alleles manifest in: A1-7 lateral transverse muscle. The phenotypic classes of alleles include: immune response defective; viable; majority die during embryonic stage; long lived; partially lethal - majority die; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 18-24 hour embryonic stages.
Coordinates
chr2R:19425113-19430564:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
45
chr2R:19426347-19426391
+
1.24
89.66
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000092529 CAPN3 2-to-2
Human hg38 ENSG00000135773 CAPN9 2-to-2
Human hg19 ENSG00000092529 CAPN3 2-to-2
Human hg19 ENSG00000135773 CAPN9 2-to-2
Mouse mm10 ENSMUSG00000031981 Capn9 2-to-2
Mouse mm10 ENSMUSG00000079110 Capn3 2-to-2
Mouse mm9 ENSMUSG00000031981 Capn9 2-to-2
Mouse mm9 ENSMUSG00000079110 Capn3 2-to-2
Rat rn6 ENSRNOG00000003468 Capn8 2-to-8
Rat rn6 ENSRNOG00000020389 Capn12 2-to-8
Rat rn6 ENSRNOG00000026025 Capn11 2-to-8
Rat rn6 ENSRNOG00000032375 Capn13 2-to-8
Rat rn6 ENSRNOG00000034015 Capn2 2-to-8
Cow bosTau6 ENSBTAG00000008868 CAPN3 2-to-1
Chicken galGal4 ENSGALG00000009050 CAPN3 2-to-1
Chicken galGal3 ENSGALG00000009050 CAPN3 2-to-1
Zebrafish danRer10 ENSDARG00000012341 capn9 2-to-3
Zebrafish danRer10 ENSDARG00000041864 capn3a 2-to-3
Zebrafish danRer10 ENSDARG00000043035 capn3b 2-to-3