DreEX6023035 @ danRer10
Exon Skipping
Gene
ENSDARG00000018032 | scn8ab
Description
sodium channel, voltage gated, type VIII, alpha subunit b [Source:ZFIN;Acc:ZDB-GENE-060906-2]
Coordinates
chr6:39412255-39420909:-
Coord C1 exon
chr6:39420433-39420909
Coord A exon
chr6:39413100-39413217
Coord C2 exon
chr6:39412255-39412409
Length
118 bp
Sequences
Splice sites
3' ss Seq
GCTGTGCGTTTTTCCACTAGCTG
3' ss Score
7.66
5' ss Seq
ATGGTGAGC
5' ss Score
8.27
Exon sequences
Seq C1 exon
GTGCTGAACCTGTTCTTAGCCTTGCTGCTGAGCTCCTTCAGTGCTGATAATCTGGCTGCCACAGATGATGACGGTGAGATGAACAACCTGCAGATCTCCGTCATCCGCATTAAGAAAGGCATTGCTTGGTTCAAAATTCATGTACGGCTGCTGGTGGCCCACGTCCTGAAGAAGAAACCTCTGGAAGATGAAGACAAACCGCTTGATGACATGTATGACAAAAAACTGAACTTAATGGGCAACCACACCGGCGTGGAAATCAAATGTGGTGATCTGAACTACCCCAAGAACGGGAATGGCACCACAAGTGGCATTGGGAGCAGCGTGGGAAAGTACATGATTGATGAGGAGCCCATGTCCTTCATCCACAACCCCAACCTGACTGTACGGGTTCCCATTGCTGTTGGAGAGTCCGACTTTGAGAATCTGAACACGGAGGACTTCAGCAGCGAATCGGATGTGGAAAATAGCAAAGAT
Seq A exon
CTGGACGACACTAGCTCTTCTGAAGGAAGTACTATCGATATAAAGCCTGATGAGGAGGAGATGGCTGTGGTGGAGGTGGTGGAAGAGTACTTAGATCCAGAGGCCTGCTGGACTGATG
Seq C2 exon
CTTGTGTGGCGCGCTACAAATGTTGTGATGTGCCTATTACTGAGGGCTGGGGGAAGTACTGGTGGTTTCTGAGGAAAACTTGCTACCTCATTGTTGAGCACAACTGGTTTGAGACGCTCATCATTTTTATGATTCTTCTCAGCTCTGGAGCTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000018032-'22-19,'22-18,23-19=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.132 A=0.350 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=5.0),PF065128=Na_trans_assoc=PU(61.4=84.9)
A:
PF065128=Na_trans_assoc=FE(17.7=100)
C2:
PF065128=Na_trans_assoc=PD(20.0=84.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGGAGCCCATGTCCTTCAT
R:
GCGTCTCAAACCAGTTGTGCT
Band lengths:
250-368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]