RnoEX6034132 @ rn6
Exon Skipping
Gene
ENSRNOG00000005309 | Scn8a
Description
sodium voltage-gated channel alpha subunit 8 [Source:RGD Symbol;Acc:3638]
Coordinates
chr7:142657739-142659324:+
Coord C1 exon
chr7:142657739-142658209
Coord A exon
chr7:142658473-142658590
Coord C2 exon
chr7:142659170-142659324
Length
118 bp
Sequences
Splice sites
3' ss Seq
TCCTCTTCCTTCCTGTCTAGAAA
3' ss Score
10.07
5' ss Seq
AGGGTAAAA
5' ss Score
4.51
Exon sequences
Seq C1 exon
GTGCTGAACCTATTCCTGGCCTTGCTTCTGAGCTCCTTCAGCGCAGACAACCTGGCGGCCACAGACGACGACGGGGAAATGAACAACCTGCAGATCTCAGTGATCCGGATCAAGAAGGGCGTGGCCTGGACCAAAGTGAAGGTGCACGCCTTCATGCAGGCTCACTTCAAGCAGCGGGAGGCGGATGAAGTGAAACCCCTCGACGAGCTGTATGAGAAGAAGGCCAACTGCATCGCCAACCACACGGGCGTGGATATCCACCGGAACGGCGACTTCCAGAAGAACGGGAACGGAACCACCAGCGGCATCGGCAGCAGCGTGGAGAAGTACATCATCGACGAGGACCACATGTCCTTCATTAACAACCCAAACCTGACCGTCCGGGTGCCCATTGCTGTGGGCGAGTCTGACTTCGAGAACCTCAACACAGAGGATGTTAGCAGCGAATCAGACCCTGAAGGCAGCAAAGAT
Seq A exon
AAACTGGACGATACCAGCTCCTCAGAAGGAAGTACCATCGACATCAAGCCTGAGGTGGAAGAAGTTCCCGTGGAGCAACCTGAGGAATACTTGGATCCGGACGCCTGCTTTACAGAGG
Seq C2 exon
GTTGCGTCCAGCGGTTCAAGTGCTGCCAGGTCAACATCGAGGAAGGACTAGGCAAGTCGTGGTGGATCTTGCGGAAAACCTGCTTCCTCATTGTGGAGCACAATTGGTTTGAGACCTTCATCATCTTCATGATTCTGCTCAGCAGTGGCGCCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000005309-'44-40,'44-39,45-40=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.223 A=0.575 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=5.1),PF065128=Na_trans_assoc=PU(61.0=84.7)
A:
PF065128=Na_trans_assoc=FE(17.9=100)
C2:
PF065128=Na_trans_assoc=PD(20.2=84.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACGGCGACTTCCAGAAGAAC
R:
CTTCCTCGATGTTGACCTGGC
Band lengths:
252-370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]