DreEX6081071 @ danRer10
Exon Skipping
Gene
ENSDARG00000005775 | scn8aa
Description
sodium channel, voltage gated, type VIII, alpha subunit a [Source:ZFIN;Acc:ZDB-GENE-000828-1]
Coordinates
chr23:27348380-27353162:-
Coord C1 exon
chr23:27352692-27353162
Coord A exon
chr23:27348652-27348769
Coord C2 exon
chr23:27348380-27348534
Length
118 bp
Sequences
Splice sites
3' ss Seq
TCATCTTTCTTTTTGATCAGTTG
3' ss Score
7.69
5' ss Seq
AAGGTAAAG
5' ss Score
9.06
Exon sequences
Seq C1 exon
GTGTTGAATCTCTTCCTTGCCTTGCTGCTGAGCTCATTCAGCGCAGACAACTTGGCTGCTTCCGATGACGATGGTGAGATGAACAACCTGCAGATCGCAGTTATTCGCATTAAGAAGGGAATCGCCTGGGTGAAGGCTAAAGTTCGAGAACTGGTCAACATCATCCTCGGGAGGAAGGTCACAGACGAAGCCAAGCCGCTTGATGACATGTACGACCGTAAACTGAACTGCATTGCCAATCACACAGGTGTGGACATCAGCCGTGACCTGGACTATCAGAAAAATGGCAACGGAACTACCAGTGGCATTGGCAGCAGTGTAGGAAAATACATGATTGACGATGACCACATGTCCTTCATCCACAACCCCAACCTGACAGTATGTGTGCCCATCGCTGTGGGCGAGTCGGACTTTGAGAATCTTAACACTGAAGATTTCAGCAGCGAGTCTGAGGCAGAGGGCAGCAAAGAA
Seq A exon
TTGGATGACATCAGCTCTTCAGAGGGCAGCACCATAGATATTAAACCAGAGGTAGAGGAAGCAGTGGTGGTGGAGACGGTAGAGGAATATGTCGATCCAGAAGCTTGCTGGACTGAAG
Seq C2 exon
CTTGTATTGCCCGCTACAAGTGTTGCGATGTGCCCATCACGGAAGGCTGGGGCAAGAATTGGTGGTTTCTCCGAAAGACCTGCTATCTGATTGTGGAGCACAACTGGTTTGAAACCCTCATCATCTTCATGATCCTCCTCAGTAGTGGAGCACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000005775-'21-23,'21-22,22-23=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.089 A=0.150 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=5.1),PF065128=Na_trans_assoc=PU(61.0=84.7)
A:
PF065128=Na_trans_assoc=FE(17.9=100)
C2:
PF065128=Na_trans_assoc=PD(20.2=84.6)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACTACCAGTGGCATTGGCAG
R:
AACCACCAATTCTTGCCCCAG
Band lengths:
245-363
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]