GgaEX7011858 @ galGal4
Exon Skipping
Gene
ENSGALG00000006060 | SCN8A
Description
sodium channel, voltage gated, type VIII alpha subunit [Source:HGNC Symbol;Acc:HGNC:10596]
Coordinates
chrLGE22C19W28_E50C23:88881-90706:-
Coord C1 exon
chrLGE22C19W28_E50C23:90236-90706
Coord A exon
chrLGE22C19W28_E50C23:89712-89829
Coord C2 exon
chrLGE22C19W28_E50C23:88881-89035
Length
118 bp
Sequences
Splice sites
3' ss Seq
GGTTTTATTTTGTGTTCAAGAAA
3' ss Score
4.43
5' ss Seq
AGGGTACGT
5' ss Score
9.15
Exon sequences
Seq C1 exon
GTGCTGAACCTGTTCCTGGCTTTGCTGCTGAGCTCCTTCAGTGCAGACAACCTGGCAGCAACGGATGACGATGGGGAGATGAACAACCTGCAGATCTCTGTCATTCGCATCAAGAAGGGCATTGCCTGGACCAAGGCGAAAGTGCGTGAATTCATGCAGGCTCACTTCAAGCAGAGAGAGGCAGATGAGGTCAAACCCTTGGACGAGCTGTATGACAAGAAGGTGAACTGCATTGCCAACCACACGGGGGCTGATATCCACAGAGACATCGATTATCAGAAGAACGGCAATGGCACAACCAGTGGAATTGGGAGCAGCGTGGAGAAATACATCATCGATGAAGACCACATGTCCTTCATCAACAACCCCAACCTCACCGTCCGGGTGCCTATTGCTGTCGGGGAGTCAGACTTTGAAAATCTCAACACAGAAGATTTCAGCAGCGATACAGACCCTGATGGCAGCAAAGAG
Seq A exon
AAACTGGATGATACCAGCTCCTCCGAAGGCAGCACCATTGATATAAAGCCTGAAGTGGAAGAAGTCCCTGTGGAGGCACCAGAAGAGTATCTGGACCCGGATGCATGCTTCACTGAGG
Seq C2 exon
GTTGCATGCAGCGCTGTAAGTGTTGTCAGGTCAATATTGAGGAGGGGCTGGGGAAGTCCTGGTGGACCTTGAGGAAGACGTGTTTTCTGATTGTGGAGCACAACTGGTTTGAGACTTTCATCATCTTCATGATCCTACTGAGCAGTGGAGCTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000006060-'25-20,'25-19,26-20=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.197 A=0.550 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=5.1),PF065128=Na_trans_assoc=PU(61.0=84.7)
A:
PF065128=Na_trans_assoc=FE(17.9=100)
C2:
PF065128=Na_trans_assoc=PD(20.2=84.6)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGAGCAGCGTGGAGAAATAC
R:
ACACGTCTTCCTCAAGGTCCA
Band lengths:
245-363
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]