DreEX6026093 @ danRer10
Exon Skipping
Gene
ENSDARG00000062661 | abca4b
Description
ATP-binding cassette, sub-family A (ABC1), member 4b [Source:ZFIN;Acc:ZDB-GENE-050517-4]
Coordinates
chr2:15609279-15609792:+
Coord C1 exon
chr2:15609279-15609471
Coord A exon
chr2:15609568-15609662
Coord C2 exon
chr2:15609760-15609792
Length
95 bp
Sequences
Splice sites
3' ss Seq
TTATTTGTGATGTGATGTAGAGA
3' ss Score
4.85
5' ss Seq
CAGGTAAGC
5' ss Score
9.88
Exon sequences
Seq C1 exon
GAACATCTTTACCTGCTTAAACTCAAGCTCAGATTGGGAAGTTCCTCCAGTGTCTCCTGAGGTCAGCAACATCTTATCAAGTCCTGAATGGGATAGCAGAAACCCATCCCCATCCTGTGAATGCAGCACTGATTTGAAGCTCACTATGCTGCCAATGTGTCCTGCTGGAGCTGGAGGACTGCCACCACGCCAG
Seq A exon
AGAAAAGAGCCAACAGGGGACATTTTGCTCGACATGACAAACAGAAATATCTCTGACTACTTGGTAAAGACTTACACAAAGCTCATCAAGACCAG
Seq C2 exon
CTTGAAGAGCAAATATTGGGTGAATGAGCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000062661-'38-36,'38-35,39-36=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.200 A=0.281 C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=PU(0.3=1.5)
A:
PF126982=ABC2_membrane_3=FE(8.1=100)
C2:
PF126982=ABC2_membrane_3=FE(2.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCTCCTGAGGTCAGCAACA
R:
TGCTCATTCACCCAATATTTGCT
Band lengths:
173-268
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000566; ELM sequence: RNISDF; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]