DreEX6026094 @ danRer10
Exon Skipping
Gene
ENSDARG00000062661 | abca4b
Description
ATP-binding cassette, sub-family A (ABC1), member 4b [Source:ZFIN;Acc:ZDB-GENE-050517-4]
Coordinates
chr2:15606968-15609662:+
Coord C1 exon
chr2:15606968-15607066
Coord A exon
chr2:15609279-15609471
Coord C2 exon
chr2:15609568-15609662
Length
193 bp
Sequences
Splice sites
3' ss Seq
ACACATGTTTGTATGTGCAGGAA
3' ss Score
7
5' ss Seq
CAGGTAACA
5' ss Score
8.88
Exon sequences
Seq C1 exon
TAATGAGCAACCGTCACATCCAAAGATGAAGCACTTCATTCAGACGCTGCTGAAGGACCCTGGCATGGGAACCCGCTGTATGGCCAATCAGCCCTTAGA
Seq A exon
GAACATCTTTACCTGCTTAAACTCAAGCTCAGATTGGGAAGTTCCTCCAGTGTCTCCTGAGGTCAGCAACATCTTATCAAGTCCTGAATGGGATAGCAGAAACCCATCCCCATCCTGTGAATGCAGCACTGATTTGAAGCTCACTATGCTGCCAATGTGTCCTGCTGGAGCTGGAGGACTGCCACCACGCCAG
Seq C2 exon
AGAAAAGAGCCAACAGGGGACATTTTGCTCGACATGACAAACAGAAATATCTCTGACTACTTGGTAAAGACTTACACAAAGCTCATCAAGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000062661-'37-35,'37-34,38-35=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.059 A=0.200 C2=0.281
Domain overlap (PFAM):
C1:
NO
A:
PF126982=ABC2_membrane_3=PU(0.3=1.5)
C2:
PF126982=ABC2_membrane_3=FE(8.1=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAATGAGCAACCGTCACATCCA
R:
CTGGTCTTGATGAGCTTTGTGT
Band lengths:
194-387
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000565; ELM sequence: PNITQL; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]