DreEX6029426 @ danRer10
Exon Skipping
Gene
ENSDARG00000090724 | scn12aa
Description
sodium channel, voltage gated, type XII, alpha a [Source:ZFIN;Acc:ZDB-GENE-060908-2]
Coordinates
chr2:52310404-52315861:-
Coord C1 exon
chr2:52315744-52315861
Coord A exon
chr2:52311074-52311228
Coord C2 exon
chr2:52310404-52310577
Length
155 bp
Sequences
Splice sites
3' ss Seq
ATGTGTTGGTATCTCTCCAGTCT
3' ss Score
6.06
5' ss Seq
CTGGTAAGA
5' ss Score
9.45
Exon sequences
Seq C1 exon
GAAGTCATCAGCCTCTCTGAAGGAAGTACCGTGGATCTGAGGAAGCCTGGAGAAGATGAAGAGGAATATTCTGAGATGGCAGATGATGGCATGGATCCAGAAGAGTGTTTTCCAGAGT
Seq A exon
TCTGCATGCAGCGCTGTAAGTGTTGTAATATAAACACAACGCAAGGTCTGGGACAGATGTGGTGGAGGCTGAGGAAGACGTGCTATCAAATTGTGGAGCATAGCTGGTTTGAGACCTTCATCATCTTTATGATCCTCCTCAGCAGCGGAGCTCTG
Seq C2 exon
GCTTTTGAAGACATTTACATCGAACAGCGGAAGGTGGTGAAGGTGGTGTTGGAGTATGCTGACAAGGTTTTCAGCTACATCTTTGTACTGGAGATGTTTCTGAAGTGGATTGCGTACGGATTTAAGAAATACTTCACTAATTACTGGTGCTGGCTGGACTTCCTGATCGTGGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000090724-'20-19,'20-18,21-19=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.725 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF065128=Na_trans_assoc=FE(19.9=100)
A:
PF065128=Na_trans_assoc=PD(22.4=84.6)
C2:
PF0052026=Ion_trans=PU(17.3=67.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGATCTGAGGAAGCCTGGAG
R:
GTCCAGCCAGCACCAGTAATT
Band lengths:
246-401
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]