MmuEX6069780 @ mm10
Exon Skipping
Gene
ENSMUSG00000032511 | Scn5a
Description
sodium channel, voltage-gated, type V, alpha [Source:MGI Symbol;Acc:MGI:98251]
Coordinates
chr9:119501622-119513101:-
Coord C1 exon
chr9:119512981-119513101
Coord A exon
chr9:119512141-119512295
Coord C2 exon
chr9:119501622-119501795
Length
155 bp
Sequences
Splice sites
3' ss Seq
TCCCCCCCCCCCCCCCACAGGCT
3' ss Score
12.4
5' ss Seq
CTGGTACCT
5' ss Score
4.11
Exon sequences
Seq C1 exon
ACTCCCGAGGACAGTTACTCCGAGGGTAGCACCGCTGACATGACCAACACCGCAGACCTCCTGGAGCAAATCCCAGACCTCGGGGAGGACGTCAAGGACCCAGAGGACTGCTTCACTGAAG
Seq A exon
GCTGCGTCCGACGTTGTCCTTGCTGCATGGTGGACACGACGCAGGCCCCAGGGAAGGTCTGGTGGAGACTGCGCAAGACCTGCTACCGCATAGTGGAGCACAGCTGGTTCGAGACTTTCATCATCTTCATGATCCTGCTCAGCAGCGGAGCGCTG
Seq C2 exon
GCCTTCGAGGACATCTACCTGGAGGAGCGGAAGACCATCAAGGTTCTGCTGGAGTACGCCGACAAGATGTTCACCTATGTCTTTGTGTTGGAGATGCTGCTCAAGTGGGTGGCCTACGGCTTCAAGAAGTACTTCACCAACGCCTGGTGCTGGCTGGACTTCCTAATTGTGGAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000032511-'30-26,'30-25,31-26=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.683 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF065128=Na_trans_assoc=FE(15.2=100)
A:
PF065128=Na_trans_assoc=PD(16.7=84.6)
C2:
PF0052026=Ion_trans=PU(17.0=67.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTTACTCCGAGGGTAGCACC
R:
CCAGGCGTTGGTGAAGTACTT
Band lengths:
256-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types