DreEX6095551 @ danRer10
Exon Skipping
Gene
ENSDARG00000057169 | abca4a
Description
ATP-binding cassette, sub-family A (ABC1), member 4a [Source:ZFIN;Acc:ZDB-GENE-050517-3]
Coordinates
chr24:28548333-28549615:+
Coord C1 exon
chr24:28548333-28548522
Coord A exon
chr24:28549402-28549496
Coord C2 exon
chr24:28549583-28549615
Length
95 bp
Sequences
Splice sites
3' ss Seq
GTATTTCATTCCTGTTTCAGAGG
3' ss Score
8.7
5' ss Seq
TAGGTATTA
5' ss Score
4.71
Exon sequences
Seq C1 exon
AGAATATCCATGTAATAACATTACCACAGAGTGGGAGATGCCCCTGGTGAACCCGATGCTCATTGAGATGTTGAGCAACTCAGAGTGGACGGACATCAGTCCTTCTCCCAGCTGCCAGTGCAGCACGCCAAACAAACTCACCATGTTACCTGTGTGTCCAGAAGGTGCTGGAGGTCTTCCTCCTCCACAG
Seq A exon
AGGATTCAGTCCACTGGTGACATGTTGATGGATCTTACAGGCAGGAACATCTCTGATTATTTAGTGAAGACGTACCCAAACTTAATACGGACTAG
Seq C2 exon
CCTGAAGAGCAAGTACTGGGTGAACGAACAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000057169-'37-38,'37-36,38-38=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.188 A=0.188 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF126982=ABC2_membrane_3=PU(2.9=83.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTGAACCCGATGCTCATTG
R:
TCGTTCACCCAGTACTTGCTC
Band lengths:
173-268
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000566; ELM sequence: RNISDF; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]