HsaEX0045755 @ hg19
Exon Skipping
Gene
ENSG00000167081 | PBX3
Description
pre-B-cell leukemia homeobox 3 [Source:HGNC Symbol;Acc:8634]
Coordinates
chr9:128510829-128692124:+
Coord C1 exon
chr9:128510829-128510902
Coord A exon
chr9:128677965-128678206
Coord C2 exon
chr9:128691934-128692124
Length
242 bp
Sequences
Splice sites
3' ss Seq
CTCTCTCTCTTTCCTTGAAGGTC
3' ss Score
11.75
5' ss Seq
CAGGTCAGC
5' ss Score
7.16
Exon sequences
Seq C1 exon
GAAACATGCCCTGAACTGTCACAGAATGAAACCAGCGCTCTTCAGCGTCCTGTGTGAGATCAAAGAGAAAACAG
Seq A exon
GTCTCAGCATCAGAGGAGCCCAGGAGGAGGACCCTCCCGATCCCCAGCTAATGAGACTGGACAATATGCTTTTGGCAGAAGGGGTTTCAGGTCCTGAGAAAGGTGGGGGATCGGCGGCAGCAGCTGCAGCCGCGGCAGCCTCTGGAGGTTCTTCAGATAACTCTATTGAACACTCAGATTACAGAGCCAAATTGACCCAGATCAGACAAATCTATCACACAGAACTGGAGAAATATGAACAG
Seq C2 exon
GCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAGAGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAACAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167081-'3-22,'3-20,19-22
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.146 A=0.696 C2=0.204
Domain overlap (PFAM):
C1:
PF037928=PBC=PU(10.1=94.1)
A:
PF037928=PBC=PU(50.0=98.4),PF040917=Sec15=PU(45.9=43.8),PF070286=DUF1319=PU(37.2=50.0),PF083976=IMD=PU(23.9=40.6)
C2:
PF037928=PBC=PD(48.4=95.3),PF040917=Sec15=PD(50.8=48.4),PF070286=DUF1319=PD(60.5=81.2),PF083976=IMD=FE(57.8=100),PF0004624=Homeobox=PU(0.1=0.0)
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GAAACATGCCCTGAACTGTCAC
R:
ACCTTGATCTTAAAATCATAACTGCT
Band lengths:
252-494
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)