MmuEX0033851 @ mm9
Exon Skipping
Gene
ENSMUSG00000038718 | Pbx3
Description
pre B cell leukemia homeobox 3 [Source:MGI Symbol;Acc:MGI:97496]
Coordinates
chr2:34068772-34226417:-
Coord C1 exon
chr2:34226344-34226417
Coord A exon
chr2:34079925-34080166
Coord C2 exon
chr2:34068772-34068962
Length
242 bp
Sequences
Splice sites
3' ss Seq
GTCTTTCTCTCTCCTTGAAGGTC
3' ss Score
11.8
5' ss Seq
CAGGTCAGC
5' ss Score
7.16
Exon sequences
Seq C1 exon
GAAACATGCTCTGAACTGTCACAGAATGAAACCGGCGCTCTTCAGCGTCTTGTGTGAGATCAAAGAGAAAACAG
Seq A exon
GTCTCAGCATCAGAGGAGCCCAGGAGGAAGACCCTCCCGACCCCCAGCTAATGAGACTGGACAATATGCTTTTGGCAGAAGGGGTTTCAGGTCCTGAGAAAGGTGGGGGATCGGCGGCAGCAGCTGCAGCCGCGGCAGCCTCTGGAGGTTCTTCAGATAACTCTATTGAACACTCAGATTACAGAGCCAAATTGACCCAGATCAGACAAATCTATCACACAGAACTGGAGAAATATGAACAG
Seq C2 exon
GCATGTAATGAATTCACAACACATGTGATGAACCTTCTCCGAGAACAGAGTAGAACGCGTCCCATTTCCCCGAAAGAGATCGAAAGGATGGTGGGCATCATCCATCGGAAATTTAGTTCCATTCAGATGCAGCTCAAGCAAAGCACGTGTGAAGCAGTTATGATTTTGAGATCAAGGTTCCTTGATGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000038718_CASSETTE1
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.161 A=0.733 C2=0.200
Domain overlap (PFAM):
C1:
PF037928=PBC=PU(29.6=94.1)
A:
PF037928=PBC=FE(40.6=100),PF040917=Sec15=PU(36.4=34.6),PF070286=DUF1319=PU(45.4=54.3)
C2:
PF037928=PBC=PD(31.0=95.3),PF040917=Sec15=PD(61.0=73.4),PF070286=DUF1319=PD(52.6=79.7),PF0004624=Homeobox=PU(0.1=0.0)
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GAAACATGCTCTGAACTGTCACA
R:
ACCTTGATCTCAAAATCATAACTGCT
Band lengths:
252-494
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types