HsaINT0027463 @ hg19
Intron Retention
Gene
ENSG00000092529 | CAPN3
Description
calpain 3, (p94) [Source:HGNC Symbol;Acc:1480]
Coordinates
chr15:42695939-42700522:+
Coord C1 exon
chr15:42695939-42695975
Coord A exon
chr15:42695976-42700408
Coord C2 exon
chr15:42700409-42700522
Length
4433 bp
Sequences
Splice sites
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
3' ss Seq
CTCCTCCCTCCTCTCTCCAGCCC
3' ss Score
10.36
Exon sequences
Seq C1 exon
GGAAGTTGAAAATACCATCTCCGTGGATCGGCCAGTG
Seq A exon
GTGAGTGGTTTAGATCTTCTGTGCGAAAAGTCCAGAGGGTCCCCTTCCCTGACCATGCAGGGGACAGATGGTGCAGGGGAGAATGGGCACTGGCAGAGGGAATGGGAGTCTGGGCTGTGCTGAGCAGTCCCTCCTTGGCACTGCAAATCCTACTTTGGCATGGCCAGAAGTAATCGGCCTTAAGCACCGGGGGCCATTGAGGCAGTTCAGGGGCTGGGAAATATGGAAGAGGGTCCTGGAAAGGAGAAGCAATTTGAACAATCGGAGGGAACAAGGCCACAGGAAGGGATGACAAGAGCCGCAGCGAACACTGGATTCTGAGACTGGATAACATTGGATTTCACACATAGAGAAAAGAAAGTAAGCTGGTGCCGGACCTGGTGTTGACACTTGGATCCTCCACTTACCAGCGGGGTGACCTGGACAATTTCTGTAATCCCTCTCACTCAGTTTCCTACTCAGTAAAACGGGGATGATAATGTGCCTTGCAAGGCTTTTGTGAGGCTTCATCAATGAGGTGATGTATGTGAAGTGTCTGGCACAGCATGGGCACTCAAACAGAGGTGCTTTTTCACACTTTACACCTTACAAGGTACTTTTCACATGTGTCATCGCGATACTTGCAAGGTTGCTGAGAGGTAGATGGGGTTATAATCCCTGGTGTTCAAGAAAGGAAGCAGAGGCTCAATGGGGTTGAATGACTTCTCTGAGTTCACAGAGCTCAGTAAGTGGCAGGGTTGGAACTCACATTCAGACTCTCTGACTCCAGACTTAGGTTTTTCCGCACCTCCACGCTGAGGCCAGCCCCAGGCAGTGAGAAGCCCAAAGTCCGAAGCACAGAGTGCTGTGTGTTGGGCTCTGTGTGTTGAGGAGTCTTGTGACTGCCTTGGGGCTTTGGGCTGTAGTCAGCTGACAGTCCTTTGTGCTCTGTGGGGATGACGTAGGCCAATGGGAGGACAAATGCCCCTCTGAACTGTCTTCTGGGCAGTGACAGTCATGGTCATAATCCTGACCCTGAGCCAGTGCCAGGTCTCCAAGTGCCTTCTGAATGACCACAGGCGATTGGTTTTAGTGGTAGGTGTGTGGGGATCTGTTCTGGTCATCTGGATGCTGGTCATCGGTGTGCAGTATTGATCAGGACCTGCAAACCCAAAAGCTTATGGGAGCTGGCACGTCACGTGAGTAGAGCAGGCAGGTGCAGGGGTTTTGATGTCCCTGCACTGACACAGTTGTCTGCAGTTCTCAATTGACATTTCGCTCCAGTGTCGAGGGTCAACAGGAATGTTGGGGCGTGGGGCAATCTGGAAGACACAGGGAGCAGGGCCCTTGGCTCAGCTGATAGTTGCCGCAGGGATTACAGGCCCAGGGCAGCCTGCCACAGCTGGGGCTTTTACCAAAGAAAATCTCCCTATGTTAAATGCTTGCTCAAAAATTTTTAAAAAATATTCTGTAAGTCAAAATCCATTGTTAGGTCAGTTTGAGAGAGCCATGTTTTTGGTGTTTTAGTAACCAATTTCATTTTTTTATTATTTATTTATTTGTTTATTTTTGAGACGGAGTTTCACTCTTGTCACCCAGGCTGGAGTGCAATGGCATGATCTCAGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGAGATTACAGGTGCCCACCATCACGCCTGGATAATTTTTGTATTTTTTAGTCGAGATGGGGTTTCACCATGTTGGCCAGGATAGTCCTGAACTACTGACCTCAGATAATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCAGCACGCCCGGCCACCAATTTCATTTTTTAAAAAAGGAAGAAAGAAAACCTTAGCCAGAAGATCTTTTTCCTTGCCATATGCAGTAAGAGTAGATTATAAAAACAAAGTCAGAGCAGTCACTGGTGTCTGGGCATGGAGGAGAAAGAAGAATTCTCTTCTCCCTTCACCCTCCATGCCCCTTTTTGGCTCCATGTGATTCAGATTTCTGGACCCTGGAGCCCCACCCCAAGCTAAAGACCAGGATACAGGGAAGCCAAAAGCCACTGGCGGTTCTGAGAACTTACTTTTCACTTATTCTGCATTTACTGTTTCCTTTTCTTATGCAGAAAAAGAAAAAAACCAAGGTAGGTGTGTGGGTAGAGAGCATGAAGTGTGTGTACTCATGCATATGTATGTGCATGCATGTGAAGTGTGCATGTGTGAGCTCATATGCATCCATGCACCAGACTTGCCTCTTCCTCCCCCTCCTTCCTGAGCTTCTGCTGGGGCCGAGCGTGCAGTAATGACAACTACGATTTGCTGGGGGAAGGCTACGTGCCAAGCACTCTTTTAGGTGCTTTCCATGATTAATTCCTTCCTCACAACAGCCCTATGAGATTAGTACTATAACTATCCCCATTTTCAGAGGGAGAAAAGGTACAGACTTGACTAACTTGCCCAAGGCCACACAGCCAGAGAGGGGCAGAGCCAGTACTTAGAGCCAGGCAGTCTGGGTCCAGAGTCCGTGTCCTGAACCACAAGAGGCCATCATACACCATCAGATTTGGTGCTAGCATTTCTGGTGGTGCCTGGTGGTGATGGATCCATCACAGGGGTCCTCCAGGTACTGGTGCTGGCCCAGACCAGAGCTGACACTCCTCAGGCACTACCACATTCCAGGCACTGTGCTTGGGGTCAGTCCCTCTCTTTTTTTTCCCCCCCAATTATAACAGTATCTACAAAGTAGGTGCTGTTATTTTTCCCCTTTCACAGGTGAGATAGACTCAAAGAAGTGAACTTGCCCAAGGAACAGAACTAATGAGTGGGGAAAATGGAACTGGAAACCATGTCTGTTTACTCCAAAACCTGTGTTTCTTGCCCTCTTTCTCTGATGCCAGCCCCCTACACTTCAAGGCCTGTGTTGTCCAGACCCACACTCGGGCCTGCCAGTGTGTGCCTGGCAGGGATGCTCCATGGCCACACCATATCCATCCTACACATCCCCCCTCAGACTGTGACCTCCATTTGCTCTGGGATCCCCACAAGCTTCAGCTGCTTGAGCAAGACACTGCTTAGAAGGCAGAGCAAGCCAAGGCCTCTGGGGCCTGCTGGGAGCCAAAGCTGGGGAGCCGTTTCCACGGGTCTATCTGCTTGAGCTGTCCTAGATGAGCAGCATGGAAGGGCAGTGGTGCATGAGTCCAGGCGGGCTGCTTTTCTGCTCCGAGAGGCTCTGCCTGCCCAGTTGTTCTCTGCATTGCAGCCTCAATCCCCACAGCCTTGCCTTCCCCCGGCTTTCCCTACAGGTGCACCGCATCCACAGTGTTGGCACCATGCAGCAGCCGCTCTCCGTCCTTTTCATATCCTTGTCACTTGCACGAGCATGTCTTGAAAATATCCCTTGTTTGTGTAGCATCTTAAATGTTTTTGCAGTATGATTTTGCATTCAGTATCTCATTTGATCCCCACAAGAGCCCTATGAGGAGGGAAAGCAGATTTTACCATTAAAGGATGAGTAAACTGAGGCCAGAGAGGATATTTTTGGTTTTTTTTGAGACAGTCTCACTCTGTCACCCAGCCTGGAGTGCAGTGGCTTGATCTTGGCTCACTGCAAGCTCCACCTCCCATGTTCACACCATTTTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACCCACCACCACACCCAGCTAATTTTTTTGTATCTTTAGTAGAGATGGGGTTTCACCCAGTTAGCCAGGATGGTCTTGATCTCCTGACCTTGTGATCTGCCTGCTTCGGCCTCCTAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGCCAGAGAGGATATTTCTTATATGAGGGGCAGGGCTGGGATTCCAGCCCAGTGTTCTGATGGCTCACCCACTGACCATGCCACTAATCCGTGTCCTTTTTCAATCTATACTTTGCAGGGTTGTAGAGGTTCCTTTGAGGTGCCTCAGTAGCTGCCATGGTGATGTGGGGTGCTGAGGGCAAAGAGCTCTGTTCTCATTAATCAGAGAAGCTTGTGTTTTTATATACACCATGTTTCTGCAGGAAATTTAATTTGAACAGTGTTTCCATCTGGAAAAAAAAAAGTCTACAAAATACTTGACAATCACTGCACTAGATCATGCTGCTTTTAGCATTCTTAGCATTTCACGTGCTGAGCTCTCAATACTCTACCATGAGGAGGGATGGAGTGGGTATGAAAAGATAAAGAACTGAAGTCACACGGCTTGTCAGTGGCAGAGATAGAGCTTGAACCGAGGTTGAAGAGCTCCCGCCTATTCCTTTCCTCTTCTCACTGGATAAAGCTGCTCCAAGAGAGGTGCTGCCTCAGTGTGCCTGTTCAGACTGTAATCCTCCCTTCCTTCCTGCCTCCTCCCTCCTCTCTCCAG
Seq C2 exon
CCCATCATCTTCGTTTCGGACAGAGCAAACAGCAACAAGGAGCTGGGTGTGGACCAGGAGTCAGAGGAGGGCAAAGGCAAAACAAGCCCTGATAAGCAAAAGCAGTCCCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092529-CAPN3:NM_024344:14
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.375 A=NA C2=0.707
Domain overlap (PFAM):
C1:
PF0106717=Calpain_III=PD(0.1=0.0),PF156271=CEP76-C2=FE(12.0=100)
A:
NA
C2:
PF156271=CEP76-C2=PD(19.0=50.0)
Main Inclusion Isoform:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)