Special

MmuEX0036991 @ mm10

Exon Skipping

Gene
ENSMUSG00000029913 | Prdm5
Description
PR domain containing 5 [Source:MGI Symbol;Acc:MGI:1918029]
Coordinates
chr6:65883523-65928021:+
Coord C1 exon
chr6:65883523-65883683
Coord A exon
chr6:65886085-65886178
Coord C2 exon
chr6:65927917-65928021
Length
94 bp
Sequences
Splice sites
3' ss Seq
CCATTTTTATTCCTGTTTAGACA
3' ss Score
7.58
5' ss Seq
CAGGTATGA
5' ss Score
9.46
Exon sequences
Seq C1 exon
GTGAGAGGACTTTTAAGTGTCACCACTGTGATGCCACATTTAAAAGGAAGGATACATTAAACGTTCATGTCCAGGTGGTCCATGAAAGACACAAGAAGTACCGATGTGAGCTGTGCAATAAGGCCTTTGTCACACCTTCAGTGCTTAGGAGTCATAAGAAG
Seq A exon
ACACACACAGGAGAAAAGGAGAAAGTCTGCCCATATTGTGGCCAGAAATTTGCCAGCAGTGGGACCCTGAGAGTTCACATCCGGAGCCACACAG
Seq C2 exon
GAGAAGCCCTACCAGTGCTCAGAGTGCAGCAAGGCCTTCAGCCAGAAGCGGGGCCTCGATGAACACAAGAGGACACACACAGGAGAAAAGCCTTTTCAGTGTGAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029913_MULTIEX1-13/18=12-18
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





Show structural model

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.093 A=0.103 C2=0.280
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF134651=zf-H2C2_2=PD(57.7=27.8),PF134651=zf-H2C2_2=WD(100=50.0),PF134651=zf-H2C2_2=PU(23.1=11.1)

							
A:
PF042167=FdhE=FE(44.9=100),PF156161=TerY-C=FE(41.9=100),PF134651=zf-H2C2_2=PD(85.7=56.2),PF134651=zf-H2C2_2=PU(38.5=31.2)

							
C2:
PF134651=zf-H2C2_2=PD(53.8=40.0),PF134651=zf-H2C2_2=PU(68.0=48.6)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000133423





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000031973, ENSMUSP00000031976, ENSMUSP00000079979
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr4:120777188-120777281 
HIGH PSI
HsaEX6086005
(PRDM5)
Human
(hg19)
chr4:121698343-121698436 
HIGH PSI
HsaEX6086005
(PRDM5)
Rat
(rn6)
chr4:96767058-96767151 
HIGH PSI
RnoEX0069360
(Prdm5)
Cow
(bosTau6)
chr6:4648284-4648377 
HIGH PSI
BtaEX0028368
(PRDM5)
Chicken
(galGal4)
chr4:53697541-53697634 
HIGH PSI
GgaEX6035032
(PRDM5)
Chicken
(galGal3)
chr4:55824278-55824371 
HIGH PSI
GgaEX6035032
(PRDM5)
Zebrafish
(danRer10)
chr23:1965038-1965131 
HIGH PSI
DreEX0058022
(prdm5)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCATGTCCAGGTGGTCCATGA

				
R: 
CTCTTGTGTTCATCGAGGCCC

				
Band lengths: 
168-262

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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