Special

MmuEX0036990 @ mm10

Exon Skipping

Gene
ENSMUSG00000029913 | Prdm5
Description
PR domain containing 5 [Source:MGI Symbol;Acc:MGI:1918029]
Coordinates
chr6:65881049-65886178:+
Coord C1 exon
chr6:65881049-65881142
Coord A exon
chr6:65883523-65883683
Coord C2 exon
chr6:65886085-65886178
Length
161 bp
Sequences
Splice sites
3' ss Seq
CTGTTGACTTGTATTCTAAGGTG
3' ss Score
6.87
5' ss Seq
AAGGTAAGT
5' ss Score
11
Exon sequences
Seq C1 exon
ACCCACTCCGAGGAGAGACCTTTCCAGTGTGATGCATGTAAAGCCTTGTTCCGCACGCCCTTTTCTCTGCAGAGACACCTGTTAATCCACAACA
Seq A exon
GTGAGAGGACTTTTAAGTGTCACCACTGTGATGCCACATTTAAAAGGAAGGATACATTAAACGTTCATGTCCAGGTGGTCCATGAAAGACACAAGAAGTACCGATGTGAGCTGTGCAATAAGGCCTTTGTCACACCTTCAGTGCTTAGGAGTCATAAGAAG
Seq C2 exon
ACACACACAGGAGAAAAGGAGAAAGTCTGCCCATATTGTGGCCAGAAATTTGCCAGCAGTGGGACCCTGAGAGTTCACATCCGGAGCCACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029913_MULTIEX1-12/18=11-13
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





Show structural model

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.093 C2=0.103
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF121713=zf-C2H2_jaz=PD(8.0=6.2),PF134651=zf-H2C2_2=PU(38.5=31.2)

							
A:
PF134651=zf-H2C2_2=PD(57.7=27.8),PF134651=zf-H2C2_2=WD(100=50.0),PF134651=zf-H2C2_2=PU(23.1=11.1)

							
C2:
PF042167=FdhE=FE(44.9=100),PF156161=TerY-C=FE(41.9=100),PF134651=zf-H2C2_2=PD(85.7=56.2),PF134651=zf-H2C2_2=PU(38.5=31.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000031976





     
                   









    
Main Skipping Isoform:
ENSMUSP00000079979





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000031973, ENSMUSP00000133423
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr4:120781143-120781303 
HIGH PSI
HsaEX6086004
(PRDM5)
Human
(hg19)
chr4:121702298-121702458 
HIGH PSI
HsaEX6086004
(PRDM5)
Rat
(rn6)
chr4:96764468-96764628 
HIGH PSI
RnoEX0069369
(Prdm5)
Cow
(bosTau6)
chr6:4644750-4644910 
HIGH PSI
BtaEX0028367
(PRDM5)
Chicken
(galGal4)
chr4:53696376-53696536 
HIGH PSI
GgaEX6035033
(PRDM5)
Chicken
(galGal3)
chr4:55823113-55823273 
HIGH PSI
GgaEX6035033
(PRDM5)
Zebrafish
(danRer10)
chr23:1977988-1978148 
HIGH PSI
DreEX6078718
(prdm5)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACCCACTCCGAGGAGAGACC

				
R: 
GTGTGGCTCCGGATGTGAAC

				
Band lengths: 
186-347

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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