Special

MmuEX0036989 @ mm10

Exon Skipping

Gene
ENSMUSG00000029913 | Prdm5
Description
PR domain containing 5 [Source:MGI Symbol;Acc:MGI:1918029]
Coordinates
chr6:65870312-65886178:+
Coord C1 exon
chr6:65870312-65870469
Coord A exon
chr6:65881049-65881142
Coord C2 exon
chr6:65886085-65886178
Length
94 bp
Sequences
Splice sites
3' ss Seq
TCAGTATCTTCCTTCTGCAGACC
3' ss Score
9.66
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
AAAAGCGGCCTTATAACTGTGAGATCTGTAACAAGTCCTTCAAGAGGCTCGATCAAGTGGGCGCCCACAAAGTGATCCACAGTGAGGACAAACCCTACCAGTGCAAGCTCTGTGGCAAGGGCTTTGCTCACAGAAACGTTTACAAGAACCACAAGAAG
Seq A exon
ACCCACTCCGAGGAGAGACCTTTCCAGTGTGATGCATGTAAAGCCTTGTTCCGCACGCCCTTTTCTCTGCAGAGACACCTGTTAATCCACAACA
Seq C2 exon
ACACACACAGGAGAAAAGGAGAAAGTCTGCCCATATTGTGGCCAGAAATTTGCCAGCAGTGGGACCCTGAGAGTTCACATCCGGAGCCACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029913_MULTIEX1-11/18=10-13
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





Show structural model

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.038 A=0.000 C2=0.103
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF144711=DUF4428=PD(2.0=1.9),PF134651=zf-H2C2_2=PD(57.7=28.3),PF121713=zf-C2H2_jaz=PU(84.0=39.6)

							
A:
PF121713=zf-C2H2_jaz=PD(8.0=6.2),PF134651=zf-H2C2_2=PU(38.5=31.2)

							
C2:
PF042167=FdhE=FE(44.9=100),PF156161=TerY-C=FE(41.9=100),PF134651=zf-H2C2_2=PD(85.7=56.2),PF134651=zf-H2C2_2=PU(38.5=31.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000031976





     
                   









    
Main Skipping Isoform:
ENSMUSP00000079979





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000031973, ENSMUSP00000133423
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr4:120784998-120785091 
HIGH PSI
HsaEX6086003
(PRDM5)
Human
(hg19)
chr4:121706153-121706246 
HIGH PSI
HsaEX6086003
(PRDM5)
Rat
(rn6)
chr4:96762506-96762599 
HIGH PSI
RnoEX0069368
(Prdm5)
Cow
(bosTau6)
chr6:4640780-4640873 
HIGH PSI
BtaEX6029851
(PRDM5)
Chicken
(galGal4)
chr4:53695094-53695187 
HIGH PSI
GgaEX6035034
(PRDM5)
Chicken
(galGal3)
chr4:55821831-55821924 
HIGH PSI
GgaEX6035034
(PRDM5)
Zebrafish
(danRer10)
chr23:1991353-1991446 
HIGH PSI
DreEX0058021
(prdm5)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCCACAGTGAGGACAAACCCT

				
R: 
TCCGGATGTGAACTCTCAGGG

				
Band lengths: 
168-262

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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