DmeEX0002286 @ dm6
Exon Skipping
Gene
FBgn0259221 | CG42321
Description
The gene ATPase 8A is referred to in FlyBase by the symbol DmelATP8A (CG42321, FBgn0259221). It is a protein_coding_gene from Dmel. It has 15 annotated transcripts and 15 polypeptides (12 unique). Gene sequence location is 2R:13414978..13439051. Its molecular function is described by: ATP binding; magnesium ion binding; ATPase-coupled intramembrane lipid transporter activity. It is involved in the biological process described with: phospholipid translocation. 25 alleles are reported. The phenotype of these alleles manifest in: larval multidendritic class IV neuron. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, during late pupal stages, in adult male stages.
Coordinates
chr2R:13414978-13419085:-
Coord C1 exon
chr2R:13418987-13419085
Coord A exon
chr2R:13415875-13415957
Coord C2 exon
chr2R:13414978-13415615
Length
83 bp
Sequences
Splice sites
3' ss Seq
CTCAAAAATTAACCCAACAGATT
3' ss Score
3.95
5' ss Seq
CGCGTGAGT
5' ss Score
8.4
Exon sequences
Seq C1 exon
CGTACATAATACCGTGTTTAAGACACTGACGGAGGCTGTTCGCGAAACGGAGATCCGACGCAGCGACATCTCCGAAGTGATGAACGAACCGCGATCTTC
Seq A exon
ATTCACGGAAACGGCCCGGCTGCTACGTAATGTCTTTACCCGTCGTGCCAACACGAGAGTCGAAACGGATCTCGAGCTATCGC
Seq C2 exon
ATGGCTATGCGTTTTCCCAGGAGGAGGGCGGAGCTGTGCCGCAGTCTATCATTATACGTGCCTATGATACGAATCTGCCAAAGCCCGAGGGTAACTAAACCGAAAACGATGGGACTCTGGATCTCACGGTGCACATGTATATAGGAGAACGCAAGGAGCTACGATTTCGATTCACATTGGTATATATTTAGAGCACACTTCTGGTAGGCCAAACTAAAAAAACACACAAAACACATCACATTTATTATCTATGTGTCTTACACCAGCAGTAATTGAAAAACATTTCGTAGACGCCACTAAACATTTGAATATTGCGCTTATATGTAAGTTTATCTTTCTATTTGCTGTTATTTATTTTGTAAGATCGCGAGGAAAAAAAACACATTTAAGAGGCTAGAGTTCGGTTTTGTTTTTATTTTTTGTATCTGTCCCCTTGTCCGCGGCGCAGCTTTGTGATACGGATACAGACTTGCATTCTTTTTTAAAAAAGTCTATCTCTA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0259221-'22-27,'22-26,26-27
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.029 A=0.000 C2=0.120
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0289033

Main Skipping Isoform:
FBpp0297637

Other Inclusion Isoforms:
FBpp0289032, FBpp0289039, FBpp0289040, FBpp0289041
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TAAGACACTGACGGAGGCTGT
R:
CGGGCTTTGGCAGATTCGTAT
Band lengths:
168-251
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)