DmeEX6009147 @ dm6
Exon Skipping
Gene
FBgn0263120 | Acsl
Description
The gene Acyl-CoA synthetase long-chain is referred to in FlyBase by the symbol DmelAcsl (CG8732, FBgn0263120). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (4 unique). Gene sequence location is 2R:8665813..8683022. Its molecular function is described by: long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. It is involved in the biological process described with 11 unique terms, many of which group under: developmental process; multicellular organism development; cell development; cell communication; lipid storage. 52 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; adult segment; embryonic abdominal segment 6; epithelial cell; cell. The phenotypic classes of alleles include: lethal; lethal - all die before end of larval stage; increased mortality; phenotype.
Coordinates
chr2R:8680012-8681048:+
Coord C1 exon
chr2R:8680012-8680486
Coord A exon
chr2R:8680549-8680721
Coord C2 exon
chr2R:8680785-8681048
Length
173 bp
Sequences
Splice sites
3' ss Seq
AACTATTATTTTTCTTGCAGACT
3' ss Score
8.77
5' ss Seq
ACTGTAAGT
5' ss Score
8.59
Exon sequences
Seq C1 exon
AGCACGTTCCACCCAAGGGAGATGACATTGCCATTATCATGTACACTTCCGGATCCACTGGCACACCTAAGGGTGTCCTCCTCTCGCACAAGAACTGCATTGCGACAATGAAGGGATTTGTTGATATGGTGCCTATCTATCCGGATGATGTACTGATCGGATTCCTGCCCCTGGCTCACGTTTTTGAATTGGTTGCGGAAAGTGTGTGTCTCATGACTGGCGTTCCAATTGGCTACTCGACCCCCTTGACTCTGATCGACACTAGCAGCAAGATCAAACGCGGGTGCAAGGGCGATGCCACCGTCCTGAAGCCCACCTGCATGACTTCGGTGCCGCTGATATTGGATCGCATTTCCAAGGGTATTAACGACAAGGTTAACTCTGGCTCGGCGTTCAAGAAATCACTCTTCAAATTCCTTTACCAGTACAAAGTCAAGTGGGTGCAGAGGGGGTACAAGACGCCGCTGATTGATAA
Seq A exon
ACTGGTGTTCAAGAAGGTGGCAAAGCTAATGGGTGGCAAAGTGCGCATTATCATGTCTGGCGGAGCGCCTCTGTCAGCAGATACACATGAGCAGATCAAGACCTGCTTGTGCTTGGAGCTGATTCAGGGCTATGGCCTTACGGAAACTACGTCTGGAGCCACTGTCATGGACT
Seq C2 exon
ACCGTGATATGACCTATGGACGCACTGGAGGACCATTAACTGTCTGCGACATCCGTCTAGTCAACTGGGAAGAAGGCAACTACCGCGTCACAAATAAACCTTATCCCCAGGGTGAGGTTCTCATTGGTGGCGAGTGTGTCTCCCAGGGATACTACAAGTTGCCCGGCAAGACCAACGAGGATTTCTTTGAGGAGGATGGACAGAGATGGTTTAAAACCGGCGACATTGGCGAAATACAAGCTGATGGCGTACTTAAGATTATTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263120-'34-19,'34-18,35-19=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0050123=AMP-binding=FE(33.5=100)
A:
PF0050123=AMP-binding=FE(12.3=100)
C2:
PF0050123=AMP-binding=FE(18.7=100)
Main Inclusion Isoform:
FBpp0305216
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0087779, FBpp0087780, FBpp0087781, FBpp0099845, FBpp0099846, FBpp0099847, FBpp0099848, FBpp0099849, FBpp0099850
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGGTTAACTCTGGCTCGGC
R:
ACACTCGCCACCAATGAGAAC
Band lengths:
242-415
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)