DmeEX6021980 @ dm6
Exon Skipping
Gene
FBgn0013812 | Dhc93AB
Description
The gene Dynein heavy chain at 93AB is referred to in FlyBase by the symbol DmelDhc93AB (CG3723, FBgn0013812). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:21024580..21042499. Its molecular function is described by: ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding; ATP binding; dynein light intermediate chain binding. It is involved in the biological process described with: microtubule-based movement; sensory perception of sound; cilium movement. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: auditory perception defective; neurophysiology defective; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected. Peak expression observed in adult male stages.
Coordinates
chr3R:21040405-21041130:-
Coord C1 exon
chr3R:21040978-21041130
Coord A exon
chr3R:21040711-21040922
Coord C2 exon
chr3R:21040405-21040646
Length
212 bp
Sequences
Splice sites
3' ss Seq
CCAATCGGTGATTTCCGCAGCTC
3' ss Score
6.42
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
AGTTCACATTTTGGAACAATCGCCTCAAGAATCTGTCGTTCATCTACGACCAGTTGCGCAACGAGCGCATTCGTGCCATGGCCCTGATACTGGAGTACTCGATGAGTGCCTACCATCCGTGTTTCCAGACCCTCTTCAAGAACGTCGTTACGG
Seq A exon
CTCTGGCGGAGGCAAAGGACATAACACTCTATTTGAACCCCCTGAAGCGCCCACTTCAGCACCTGGAGGAGATTGATTTCGCCGAGTGCAAGCCGCTGCTCATTCCGTTCATGAATACGGTGGGCATTTTGTGGGGCAACTCACGCTACTATTGCCAGTCGGCGAAAATAACCGTGCTGTTGCAGGAAATATGCAACTTGATTATACACCAG
Seq C2 exon
GCCAAGAGATACTTGGATCCCTCGTCCATATTCCACAGCGATATCGACGAGGCCATGCAGCGACTCACCCTGTCCATACAGATACTAAAGTTCTTTCGGGAGCTATTCGACTACTACAAGGAACGATTGGCCACGTTCTTCACGGAACCCGAGGAGCGGCCGCCGATTTTATGGACTTTTCATCCAAATTCAGTTTTCAAGCGCTTTAATGCCTTCCTCGAACGCCTCACAACAATTCAATG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0013812-'1-2,'1-1,2-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF083857=DHC_N1=FE(8.7=100)
A:
PF083857=DHC_N1=FE(12.0=100)
C2:
PF083857=DHC_N1=FE(13.7=100)
Main Inclusion Isoform:
FBpp0307750
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0271744
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TTCATCTACGACCAGTTGCGC
R:
AAGTCCATAAAATCGGCGGCC
Band lengths:
293-505
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)