DmeEX6023850 @ dm6
Exon Skipping
Gene
FBgn0039581 | Moca-cyp
Description
The gene Moca-cyp is referred to in FlyBase by the symbol DmelMoca-cyp (CG1866, FBgn0039581). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:28340334..28345169. Its molecular function is described by: cyclosporin A binding; peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: protein peptidyl-prolyl isomerization; protein folding; mRNA splicing, via spliceosome. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
Coordinates
chr3R:28341372-28342626:+
Coord C1 exon
chr3R:28341372-28342214
Coord A exon
chr3R:28342280-28342419
Coord C2 exon
chr3R:28342479-28342626
Length
140 bp
Sequences
Splice sites
3' ss Seq
GTCATATTTTCTCGTTGCAGTAT
3' ss Score
7.89
5' ss Seq
AGGGTACGA
5' ss Score
7.38
Exon sequences
Seq C1 exon
CCGCCATCCCAGCATCCCTAGTGCATTTGGTCTGTGGGTCCAAAAACCAAGCGAAAGACGATGCAGGTCTTTCAGCTCCATGGTCTTTGGTCCCTGGGCCTGGGTCTCAGTGTGTGTCTCAATCTCTCTCTCTCTCGCTGTCGGCTCCTTGTGGATCTTTGCGGGAATCTTGGGCTGGATCCTCACGATGGATCTGCCAGATGACAATGTGCTGGCCATGGCCAGCGGCAGCGGCTCTTGCGGTTGGTGGCTTGCCAAAATCCTGTGTGCCACCTCTGCCTACACACCTAGAAACCTTTAAACTTTGTTGCACATGACATTGTCTCCGCCACAACCGACAACAATAACAACAACAACAACTGAAACAACAACAACAACACCGATTTCAACTACAACTGCCTACTGCAGCCCAACAACCAGTTAGCCAAAGTGTAAAGAATATTTTTCTCTTCTTCTGTTTCTCATTGTAGTACAACACAGCCTGCGCCACATTTGGACAA
Seq A exon
TATCCATGTTGTATTCGGCCAAGTTATATCCGGTCAGGAGTTGGTGCGCCAATTGGAGGGCTTGCCTGTCGATCGGAACTCACGCCCGCTGCAGGATGCAGCCATTGCCAACTGCGGTGAACTAGTTAGACAGACAAAGG
Seq C2 exon
CCAAAAAGGAGAAGAAGCACAAGAGGCGCTCCACGGCCACCGAAGATTCAAACAGCGAGGAAAGTGAGGCTGAAGCAAAGGTCGTGCGCAAGGCCAAGAAGAAAAAACGCAGCCGCAAAGATACGAAGTCGCAAAGCGATAGCGAAGA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0039581-'4-7,'4-6,5-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.317 A=0.708 C2=1.000
Domain overlap (PFAM):
C1:
PF0016016=Pro_isomerase=FE(17.5=100)
A:
PF0016016=Pro_isomerase=PD(24.1=83.3)
C2:
NO
Main Inclusion Isoform:
FBpp0084655
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CATGACATTGTCTCCGCCACA
R:
GCCTCACTTTCCTCGCTGTTT
Band lengths:
258-398
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)