DreEX6023028 @ danRer10
Exon Skipping
Gene
ENSDARG00000018032 | scn8ab
Description
sodium channel, voltage gated, type VIII, alpha subunit b [Source:ZFIN;Acc:ZDB-GENE-060906-2]
Coordinates
chr6:39440960-39442503:-
Coord C1 exon
chr6:39442362-39442503
Coord A exon
chr6:39441322-39441528
Coord C2 exon
chr6:39440960-39441235
Length
207 bp
Sequences
Splice sites
3' ss Seq
CATGTCCTTCTTTCTCTTAGACT
3' ss Score
9.55
5' ss Seq
CAGGTACAC
5' ss Score
7.29
Exon sequences
Seq C1 exon
ACGGTGTCCGGAGGGCTATACTTGCATGAAGGCTGGACGCAACCCAAACTATGGCTACACAAGCTTTGACTCCTTCGGTTGGGCTTTTCTTGCTCTCTTCCGACTGATGACACAAGATTTCTGGGAGAATCTGTACCAGCTG
Seq A exon
ACTCTACGAGCTGCGGGAAAAACATACATGATCTTTTTCGTTCTGGTGATCTTTGTGGGATCGTTCTACCTGGTGAATCTGATCCTGGCTGTGGTGGCCATGGCCTATGAAGAACAGAACCAGGCCACCATTGAGGAGGCTGAACAGAAGGAAGCGGAGTTTAAAGCCATGCTGGAGCAGCTGAAGAAACAACAGGAGGAGGCACAG
Seq C2 exon
GCCAATGCCATGGCGACTTCAGCAGGTACAGTGTCTGAGGACGCAGTGGAGGACGATGGCGGAGGGCATCTGTCCCGCAGCTCCTCTGAAGTGTCCAAACTGAGCTCCAAGAGCGCCAAGGAGCGCAGGAACAGAAAGAAGAAGTGGAGGAAAGAGCAGGAGGAGAAGGGAGACAGTGAGAAAGTAGTGAAGTCAGAATCTGATGATGGCAGCAAGAGGAGCCGCTTCCGTTTCAGAGACAACAGGCTTGGGCGGAAGGCCTCCATCATGAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000018032-'13-11,'13-10,14-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.058 C2=0.935
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(18.7=100)
A:
PF0052026=Ion_trans=PD(12.4=44.9),PF0043013=ATP-synt_B=PU(51.7=89.9),PF0310514=SPX=PU(19.6=55.1)
C2:
PF0043013=ATP-synt_B=PD(46.7=60.9),PF0310514=SPX=FE(46.9=100),PF119333=DUF3451=PU(31.7=68.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
ACTCCTTCGGTTGGGCTTTTC
R:
GCTCCTCTTGCTGCCATCATC
Band lengths:
296-503
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]