MmuEX6056589 @ mm10
Exon Skipping
Gene
ENSMUSG00000023033 | Scn8a
Description
sodium channel, voltage-gated, type VIII, alpha [Source:MGI Symbol;Acc:MGI:103169]
Coordinates
chr15:100971520-100974716:+
Coord C1 exon
chr15:100971520-100971661
Coord A exon
chr15:100972754-100972960
Coord C2 exon
chr15:100974423-100974716
Length
207 bp
Sequences
Splice sites
3' ss Seq
ACGTGGCCTTCCTCTTTCAGACC
3' ss Score
11.57
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
GCAATGCCCAGAGGGGTTCCAGTGCATGAAAGCAGGAAGAAATCCCAACTACGGCTACACCAGCTTCGACACCTTCAGCTGGGCCTTCCTGGCACTGTTCCGCCTCATGACTCAGGACTACTGGGAGAACTTATACCAGCTG
Seq A exon
ACCTTACGAGCGGCTGGGAAAACGTACATGATCTTCTTTGTCTTGGTGATCTTCGTGGGTTCTTTCTATTTGGTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTACGAAGAGCAGAACCAGGCAACACTGGAGGAGGCAGAGCAGAAAGAGGCAGAGTTCAAGGCGATGCTGGAGCAGCTCAAGAAGCAGCAGGAGGAGGCGCAG
Seq C2 exon
GCTGCTGCAATGGCCACTTCGGCGGGCACCGTCTCAGAAGATGCCATTGAAGAAGAAGGGGAAGATGGGGTAGGCTCTCCGAGGAGCTCATCTGAGCTGTCTAAACTCAGTTCCAAGAGCGCGAAGGAGCGTCGGAACCGACGGAAGAAGAGGAAGCAGAAGGAGCTCTCTGAAGGGGAGGAGAAGGGGGACCCCGAGAAGGTGTTTAAGTCAGAGTCGGAAGATGGCATGAGAAGGAAGGCCTTCCGGCTGCCAGACAATAGGATAGGGAGGAAATTTTCCATCATGAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000023033-'31-35,'31-33,36-35=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.072 C2=0.857
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(18.7=100),PF057587=Ycf1=FE(16.2=100)
A:
PF0052026=Ion_trans=PD(12.4=44.9),PF057587=Ycf1=FE(23.4=100),PF0043013=ATP-synt_B=PU(72.1=89.9),PF0310514=SPX=PU(20.3=58.0)
C2:
PF057587=Ycf1=PD(33.1=98.0),PF0043013=ATP-synt_B=PD(25.6=22.4),PF0310514=SPX=FE(49.2=100),PF119333=DUF3451=PU(31.8=68.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CACTGTTCCGCCTCATGACTC
R:
GGCCTTCCTTCTCATGCCATC
Band lengths:
293-500
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types