DreEX6081064 @ danRer10
Exon Skipping
Gene
ENSDARG00000005775 | scn8aa
Description
sodium channel, voltage gated, type VIII, alpha subunit a [Source:ZFIN;Acc:ZDB-GENE-000828-1]
Coordinates
chr23:27367992-27375456:-
Coord C1 exon
chr23:27375315-27375456
Coord A exon
chr23:27370279-27370485
Coord C2 exon
chr23:27367992-27368276
Length
207 bp
Sequences
Splice sites
3' ss Seq
ATATTGTGCTTCGTCCACAGACA
3' ss Score
10.13
5' ss Seq
CAGGTCAGG
5' ss Score
7.2
Exon sequences
Seq C1 exon
TCGCTGTCCTGAAGGTTACACATGCATGAAGGCTGGCCGTAATCCAAACTATGGCTACACCAGCTTTGACAGTTTTGGCTGGGCTTTCCTGGCTCTCTTCCGCCTCATGACGCAGGACTTCTGGGAGAACTTGTACCAGCTG
Seq A exon
ACACTGAGAGCAGCAGGGAAGACCTACATGATTTTCTTTGTGCTGGTCATCTTTGTGGGCTCCTTCTATCTTGTGAATCTGATTCTGGCTGTGGTGGCCATGGCATATGAGGAGCAGAACCAGGCCACCATGGAGGAGGCGGAGCGAAAGGAGGCGGAGTTTAAAGCCATGCTGGAACAGCTGAAGAAACAGCAGGAGGACGCACAG
Seq C2 exon
GCAAATGCAATGGCGACGTCAGCGGGAACAGTGTCTGAGGACGTGGTGGAGGATGATGGAGATGGAGAAGGGAATTTGTCCTGCAGCTCGTCTGAGATGTCTAAACTGAGCTCCAAGAGTGCCAAAGAGAGACGCAACCGCAAGAAGAAGTGGCGGCAGAAAGAGCAGGACAAAGAGAAAGGGGACAGCGAGAAGTTTGTCAAATCCGAATCAGACGATGGAAGCAGAAGGAGATTTCGTTTCCCTGATAACCGTTTGGGCCGAAGGAGTTCCATAATGAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000005775-'12-14,'12-13,13-14=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.145 C2=0.958
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(18.7=100)
A:
PF0052026=Ion_trans=PD(12.3=44.9),PF0043013=ATP-synt_B=PU(76.5=89.9)
C2:
PF0043013=ATP-synt_B=PD(21.0=17.9),PF119333=DUF3451=PU(33.0=67.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGGCTGGCCGTAATCCAAA
R:
TCTCGCTGTCCCCTTTCTCTT
Band lengths:
308-515
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]