HsaEX0066804 @ hg38
Exon Skipping
Gene
ENSG00000131323 | TRAF3
Description
TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]
Coordinates
chr14:102876358-102897401:+
Coord C1 exon
chr14:102876358-102876525
Coord A exon
chr14:102886189-102886269
Coord C2 exon
chr14:102897261-102897401
Length
81 bp
Sequences
Splice sites
3' ss Seq
AGTACTTTCTCTCTCTGTAGAAA
3' ss Score
9.74
5' ss Seq
GAGGTAGGG
5' ss Score
7.81
Exon sequences
Seq C1 exon
GTGCATTTAAAAAATGATTGCCATTTTGAAGAACTTCCATGTGTGCGTCCTGACTGCAAAGAAAAGGTCTTGAGGAAAGACCTGCGAGACCACGTGGAGAAGGCGTGTAAATACCGGGAAGCCACATGCAGCCACTGCAAGAGTCAGGTTCCGATGATCGCGCTGCAG
Seq A exon
AAACACGAAGACACCGACTGTCCCTGCGTGGTGGTGTCCTGCCCTCACAAGTGCAGCGTCCAGACTCTCCTGAGGAGCGAG
Seq C2 exon
GTTTCCTTGTTGCAGAATGAAAGTGTAGAAAAAAACAAGAGCATACAAAGTTTGCACAATCAGATATGTAGCTTTGAAATTGAAATTGAGAGACAAAAGGAAATGCTTCGAAATAATGAATCCAAAATCCTTCATTTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131323_MULTIEX2-3/7=2-7
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0148516=IBR=PD(82.3=91.1),PF0217613=zf-TRAF=PU(94.7=96.4),PF086146=ATG16=PU(22.2=53.6),PF101744=Cast=PU(1.3=3.6)
A:
PF0217613=zf-TRAF=PD(1.8=3.7),PF0314511=Sina=PU(15.4=37.0)
C2:
PF086146=ATG16=FE(34.1=100),PF101744=Cast=FE(29.9=100),PF0149614=V_ATPase_I=FE(25.1=100),PF0205011=FliJ=FE(46.5=100),PF138511=GAS=PU(32.5=80.9)
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAATACCGGGAAGCCACATGC
R:
TCGAAGCATTTCCTTTTGTCTCTCA
Band lengths:
171-252
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development